LHCGR and CHST9

Number of citations of the paper that reports this interaction (PMID 11445554)
3

Data Source:
HPRD (in vitro)

		LHCGR	CHST9
Gene Name		luteinizing hormone/choriogonadotropin receptor	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endosome Plasma Membrane Integral Component Of Plasma Membrane	Golgi Membrane Extracellular Region Integral Component Of Membrane
	Molecular Function	Luteinizing Hormone Receptor Activity Choriogonadotropin Hormone Receptor Activity Choriogonadotropin Hormone Binding	N-acetylgalactosamine 4-O-sulfotransferase Activity
	Biological Process	G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Activation Of Adenylate Cyclase Activity Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Male Gonad Development Male Genitalia Development Positive Regulation Of Inositol Trisphosphate Biosynthetic Process Luteinizing Hormone Signaling Pathway Positive Regulation Of CAMP-mediated Signaling Cognition Cellular Response To Gonadotropin Stimulus	Carbohydrate Metabolic Process Sulfur Compound Metabolic Process Pathogenesis Carbohydrate Biosynthetic Process Proteoglycan Biosynthetic Process Glycosaminoglycan Metabolic Process Chondroitin Sulfate Metabolic Process Chondroitin Sulfate Biosynthetic Process Hormone Biosynthetic Process Small Molecule Metabolic Process
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events Class A/1 (Rhodopsin-like receptors) Hormone ligand-binding receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs		Goserelin Menotropins Lutropin alfa Cetrorelix Choriogonadotropin alfa Buserelin
Diseases
GWAS		Polycystic ovary syndrome ( 22885925 21151128) Sex hormone-binding globulin levels ( 22829776)	Breast cancer ( 23535729) Dental caries ( 23259602)
Protein-Protein Interactions		11 interactors: ARRB2 CANX CGA CGB CHST9 GIPC1 GNAI2 GNAS LHB SLC9A3R1 TSHR	1 interactors: LHCGR
Entrez ID		3973	83539
HPRD ID		01073	13058
Ensembl ID		ENSG00000138039	ENSG00000154080
Uniprot IDs		P22888	Q7L1S5
PDB IDs		1LUT 1XUL
Enriched GO Terms of Interacting Partners?		Cell-cell Signaling Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Peptide Hormone Processing Hormone Metabolic Process Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Regulation Of Hormone Levels G-protein Coupled Receptor Signaling Pathway Signaling Cell Communication Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Peptide Metabolic Process Signal Transduction Platelet Activation Dopamine Receptor Signaling Pathway Secretion Positive Regulation Of Signal Transduction Protein Processing Cell Activation Cellular Amide Metabolic Process Hormone Biosynthetic Process Cellular Response To Stimulus Regulation Of Adenylate Cyclase Activity Regulation Of Synaptic Transmission Acid Secretion Positive Regulation Of Intracellular Signal Transduction Regulation Of Cyclase Activity Renal Phosphate Ion Absorption Post-embryonic Body Morphogenesis Regulation Of CAMP Biosynthetic Process Blood Coagulation Hemostasis Renal System Process Negative Regulation Of Sodium:proton Antiporter Activity Thyroid-stimulating Hormone Signaling Pathway Glutathione Transport Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Regulation Of Multicellular Organism Growth Regulation Of CAMP Metabolic Process Protein Localization Adult Locomotory Behavior Cell Surface Receptor Signaling Pathway Secretion By Cell Protein Secretion Regulation Of Protein Kinase B Signaling Response To Stimulus Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Regulation Of Body Fluid Levels Synaptic Transmission Reproductive Process	Luteinizing Hormone Signaling Pathway Positive Regulation Of Inositol Trisphosphate Biosynthetic Process Regulation Of Inositol Trisphosphate Biosynthetic Process Positive Regulation Of Inositol Phosphate Biosynthetic Process Positive Regulation Of CAMP-mediated Signaling Regulation Of CAMP-mediated Signaling Cellular Response To Gonadotropin Stimulus Activation Of Adenylate Cyclase Activity Male Genitalia Development Positive Regulation Of Adenylate Cyclase Activity Response To Gonadotropin Positive Regulation Of Lyase Activity Regulation Of Adenylate Cyclase Activity Genitalia Development Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of CAMP Biosynthetic Process Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of CAMP Biosynthetic Process Regulation Of CAMP Metabolic Process G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Regulation Of Carbohydrate Metabolic Process Male Gonad Development Male Sex Differentiation Gonad Development Development Of Primary Sexual Characteristics Cognition Sex Differentiation Reproductive Structure Development Reproductive System Development Cellular Response To Hormone Stimulus
Tagcloud ?		ancestral arose assigns booroola closely deer distance divergence duplication fecb fecundity fsh fshr fshrs gonadotrophin linkage mammalian mammals ovine probes recombinants restriction rise sheep today tsh tshr
Tagcloud (Difference) ?		ancestral arose assigns booroola closely deer distance divergence duplication fecb fecundity fsh fshr fshrs gonadotrophin linkage mammalian mammals ovine probes recombinants restriction rise sheep today tsh tshr
Tagcloud (Intersection) ?