SLC6A17 and BNIP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC6A17	BNIP3
Description		solute carrier family 6 member 17	BCL2 interacting protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Synaptic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Cell Projection Synapse Presynapse Postsynapse Glutamatergic Synapse GABA-ergic Synapse	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Envelope Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Postsynaptic Density Membrane Dendrite Mitochondrial Membrane
	Molecular Function	Protein Binding Symporter Activity Transmembrane Transporter Activity	Protein Binding Identical Protein Binding Protein Homodimerization Activity GTPase Binding Endoplasmic Reticulum-autophagosome Adaptor Activity Mitochondrion Autophagosome Adaptor Activity
	Biological Process	Monoatomic Ion Transport Sodium Ion Transport Neurotransmitter Transport Amino Acid Transport Brain Development Neutral Amino Acid Transport Glycine Transport L-leucine Transport Proline Transport Protein Catabolic Process Alanine Transport Sodium Ion Transmembrane Transport Transport Across Blood-brain Barrier	Autophagy Of Mitochondrion Mitophagy Response To Hypoxia Apoptotic Process Response To Bacterium Positive Regulation Of Autophagy Negative Regulation Of Mitochondrial Fusion Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Macroautophagy Cerebral Cortex Development Mitochondrial Protein Catabolic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Negative Regulation Of Programmed Cell Death Positive Regulation Of Protein-containing Complex Disassembly Mitochondrial Fragmentation Involved In Apoptotic Process Negative Regulation Of Membrane Potential Regulation Of Mitochondrial Membrane Permeability Autophagic Cell Death Response To Axon Injury Oligodendrocyte Differentiation Brown Fat Cell Differentiation Neuron Apoptotic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Defense Response To Virus Response To Hyperoxia Reticulophagy Substrate Localization To Autophagosome Cellular Response To Hydrogen Peroxide Cellular Response To Mechanical Stimulus Cellular Response To Cobalt Ion Cellular Response To Hypoxia Reactive Oxygen Species Metabolic Process Positive Regulation Of Mitochondrial Fission Positive Regulation Of Release Of Cytochrome C From Mitochondria Response To Oxygen-glucose Deprivation Intrinsic Apoptotic Signaling Pathway Mitochondrial Outer Membrane Permeabilization Granzyme-mediated Programmed Cell Death Signaling Pathway Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Autophagy Of Mitochondrion Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia
Pathways
Drugs
Diseases
GWAS		Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Metabolite levels ( 23823483)
Interacting Genes		1 interacting genes: BNIP3	71 interacting genes: AGTR1 AMIGO1 ARL13B BCL2 BCL2L1 BCL2L2 BIK BNIP2 BNIP3L CD3E CD47 CLDN9 CLEC7A CLN8 CMTM5 CREB3 CREB3L1 EBAG9 EBP ELOVL4 ERGIC3 FAM209A FAM241B FATE1 FBXL4 FFAR2 FXYD6-FXYD2 GPR152 GPR37 GPR42 HIF1A HIVEP1 HPN HTR2B IFNGR2 JAGN1 KTN1 LDLRAD1 LMNA MALL MAP1LC3B MS4A3 NCBP1 OPA1 PLP2 PPTC7 REEP2 RHEB RNASEK RNF24 RPRM SCN3B SEC22A SEC23A SLC31A2 SLC35B1 SLC6A17 SLC71A2 SMIM3 SPACA1 TGM2 TLCD4 TM4SF18 TMEM101 TMEM106C TMEM11 TMEM205 TMPRSS2 TMX2 TNMD ZDHHC15
Entrez ID		388662	664
HPRD ID		18061	04482
Ensembl ID		ENSG00000197106	ENSG00000176171
Uniprot IDs		Q9H1V8	Q12983 Q6NVY4
PDB IDs			2J5D 2KA1 2KA2
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Cellular Response To Cobalt Ion Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Cardiac Muscle Cell Apoptotic Process Mitochondrial Protein Catabolic Process Response To Oxygen-glucose Deprivation Regulation Of Mitochondrial Fusion Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Response To Cobalt Ion Endoplasmic Reticulum-autophagosome Adaptor Activity Striated Muscle Cell Apoptotic Process Negative Regulation Of Membrane Potential Autophagic Cell Death Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Substrate Localization To Autophagosome Negative Regulation Of Mitochondrial Fusion Positive Regulation Of Mitochondrial Calcium Ion Concentration Granzyme-mediated Programmed Cell Death Signaling Pathway Mitochondrial Envelope Negative Regulation Of Mitochondrial Membrane Potential Mitochondrial Fragmentation Involved In Apoptotic Process Mitochondrial Outer Membrane Permeabilization Mitochondrion Autophagosome Adaptor Activity Negative Regulation Of Mitochondrial Membrane Permeability Response To Hyperoxia Reticulophagy Positive Regulation Of Mitochondrial Fission Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Negative Regulation Of Membrane Permeability Muscle Cell Apoptotic Process Mitochondrial Calcium Ion Homeostasis Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria Brown Fat Cell Differentiation Regulation Of Mitochondrial Fission Positive Regulation Of Autophagy Of Mitochondrion Positive Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Membrane Permeability Positive Regulation Of Protein-containing Complex Disassembly GTPase Binding Regulation Of Release Of Cytochrome C From Mitochondria Oligodendrocyte Differentiation Response To Axon Injury Regulation Of Cardiac Muscle Cell Apoptotic Process Regulation Of Autophagy Of Mitochondrion Mitophagy Regulation Of Mitochondrial Membrane Permeability Apoptotic Mitochondrial Changes Regulation Of Membrane Permeability Cellular Response To Hydrogen Peroxide	Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Bcl-2 Family Protein Complex Protein Binding Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Mitochondrial Outer Membrane Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Mitochondrial Membrane Organization Apoptotic Mitochondrial Changes Negative Regulation Of Apoptotic Process Mitochondrial Membrane Mitochondrion Organization Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Programmed Cell Death Regulation Of Release Of Cytochrome C From Mitochondria Dendritic Cell Apoptotic Process Negative Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Apoptotic Process Golgi Membrane Negative Regulation Of Autophagy Regulation Of Programmed Cell Death Release Of Cytochrome C From Mitochondria Regulation Of Intrinsic Apoptotic Signaling Pathway BH3 Domain Binding Apoptotic Process Membrane Organization Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Programmed Cell Death Cell Death Positive Regulation Of Cell Maturation Negative Regulation Of Dendritic Cell Apoptotic Process Channel Activity Regulation Of Response To Endoplasmic Reticulum Stress Ceramide Binding Transmembrane Transport Chemical Homeostasis Mitochondrion
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?