CNNM3 and PTP4A2

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (pull down, affinity chromatography technology, affinity chromatography technology)

		CNNM3	PTP4A2
Description		cyclin and CBS domain divalent metal cation transport mediator 3	protein tyrosine phosphatase 4A2
Image
GO Annotations	Cellular Component	Plasma Membrane Membrane	Nucleus Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Membrane
	Molecular Function	Protein Binding Transmembrane Transporter Activity	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Enzyme Inhibitor Activity Protein Binding Hydrolase Activity
	Biological Process	Monoatomic Ion Transport Magnesium Ion Homeostasis Transmembrane Transport
Pathways			RAB geranylgeranylation
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Birth weight ( 31043758) Erectile dysfunction and prostate cancer treatment ( 20932654) Offspring birth weight ( 31043758)	Appendicular lean mass ( 33097823) Body mass index ( 26426971)
Interacting Genes		71 interacting genes: ACTN2 AGR2 AGR3 AKAP8L CALCOCO2 CARD10 CBY2 CCNDBP1 COG6 CYSRT1 EFEMP2 EXOSC8 FHL3 FHL5 GOLGA6L9 HNRNPK HOXA1 HSF2BP KHDRBS2 KHDRBS3 KPRP KRT31 KRT33B KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP17-1 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP4-12 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LZTS2 MDFI MID2 MTUS2 NBPF19 NOTCH2NLA P4HB PM20D2 PNMA1 PNMA2 PNMA3 PTP4A2 RBMX RBMY1F RBMY1J RBPMS RELA SRSF3 SSC4D TGM1 TNS2 TRIM27 UBE2G2 UBQLN2 USHBP1 VWC2 WWOX ZNF330 ZRANB1	13 interacting genes: AKAP8L ATF7 CARS1 CNNM1 CNNM3 DHX15 DUSP22 EWSR1 HSP90AA1 HSP90AB1 MPO RABGGTB WIPF2
Entrez ID		26505	8073
HPRD ID		07419	03348
Ensembl ID		ENSG00000168763	ENSG00000184007
Uniprot IDs		Q8NE01	Q12974
PDB IDs		5K22 5K23 5K25 5TSR 6DFD 6MN6 6WUR	5K22 5K23 5K25 6WUR
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Identical Protein Binding Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing Protein Binding Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of MRNA Metabolic Process Structural Constituent Of Skin Epidermis Nucleic Acid Binding Cytosol Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Processing	Nitric-oxide Synthase Regulator Activity Dendritic Growth Cone TPR Domain Binding Telomerase Holoenzyme Complex Assembly Magnesium Ion Homeostasis Axonal Growth Cone Chaperone-mediated Protein Complex Assembly RNA-templated DNA Biosynthetic Process MHC Class II Protein Complex Binding Telomere Maintenance Via Telomerase Histone Deacetylase Binding Disordered Domain Specific Binding DNA Polymerase Binding Telomere Maintenance Via Telomere Lengthening Protein Folding Chaperone Complex ATP-dependent Protein Folding Chaperone Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Nitric Oxide Metabolic Process Protein Tyrosine Kinase Binding Tau Protein Binding CTP Binding DATP Binding Cellular Response To Heat Hypochlorous Acid Biosynthetic Process Protein Folding Chaperone Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric Oxide Metabolic Process Cysteine-tRNA Ligase Activity Cysteinyl-tRNA Aminoacylation Double-stranded RNA Binding Neurofibrillary Tangle Assembly UTP Binding Sulfonylurea Receptor Binding HSP90-CDC37 Chaperone Complex Response To Gold Nanoparticle U2-type Post-mRNA Release Spliceosomal Complex Response To Alkaloid DNA Biosynthetic Process Response To Unfolded Protein Rho GDP-dissociation Inhibitor Binding Chromosome Organization Response To Heat Neuronal Cell Body Response To Transition Metal Nanoparticle Leading Edge Of Lamellipodium ATP Hydrolysis Activity Telomere Maintenance Melanosome Phagocytic Vesicle Lumen Rab-protein Geranylgeranyltransferase Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?