TBPL2 and DNAJB5

Number of citations of the paper that reports this interaction (PubMedID 18555775)
0

Data Source:
BioGRID (pull down, affinity chromatography technology, pull down)

		TBPL2	DNAJB5
Description		TATA-box binding protein like 2	DnaJ heat shock protein family (Hsp40) member B5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Female Germ Cell Nucleus Nucleus Cytoplasm	Nucleus Cytosol
	Molecular Function	DNA Binding RNA Polymerase II General Transcription Initiation Factor Activity	Protein Binding Unfolded Protein Binding Protein-folding Chaperone Binding
	Biological Process	DNA-templated Transcription Initiation Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Protein Folding Response To Unfolded Protein
Pathways		Germ layer formation at gastrulation
Drugs
Diseases
GWAS		Early spontaneous preterm birth ( 31194736) Pediatric bone mineral content (femoral neck) ( 28181694) Pediatric bone mineral density (femoral neck) ( 28181694) Pediatric bone mineral density (hip) ( 28181694) Platelet count ( 27863252 32888494) Testicular germ cell tumor ( 28604728)	Response to quetiapine in schizophrenia ( 29503163)
Interacting Genes		4 interacting genes: DNAJB4 DNAJB5 KPNA2 MAP4K4	11 interacting genes: ANK2 CACNA1A MRFAP1 MYBPC1 NOCT OBSCN SMAD2 SMAD3 TAF1 TBPL2 TTN
Entrez ID		387332	25822
HPRD ID		10607	07106
Ensembl ID		ENSG00000182521	ENSG00000137094
Uniprot IDs		Q6SJ96	A0A7I2RN43 O75953
PDB IDs
Enriched GO Terms of Interacting Partners?		Unfolded Protein Binding Protein-folding Chaperone Binding Response To Unfolded Protein Entry Of Viral Genome Into Host Nucleus Through Nuclear Pore Complex Via Importin Positive Regulation Of ARF Protein Signal Transduction Viral Penetration Into Host Nucleus Protein Folding Creatine Kinase Activity MAP Kinase Kinase Kinase Kinase Activity Intracellular Transport Of Virus Positive Regulation Of Focal Adhesion Disassembly Host Cell NLS-dependent Protein Nuclear Import Complex Positive Regulation Of Keratinocyte Migration Nuclear Import Signal Receptor Activity Regulation Of ARF Protein Signal Transduction Positive Regulation Of Hippo Signaling Nuclear Localization Sequence Binding Positive Regulation Of Viral Life Cycle NLS-bearing Protein Import Into Nucleus Hippo Signaling ATPase Activator Activity	M Band Protein Localization To M-band Paraxial Mesoderm Morphogenesis Sarcomere Organization Structural Constituent Of Muscle Mesoderm Morphogenesis Pericardium Development SMAD Protein Complex Trophoblast Cell Migration Heteromeric SMAD Protein Complex Embryonic Foregut Morphogenesis Nodal Signaling Pathway Co-SMAD Binding Primary MiRNA Processing Titin Binding Transforming Growth Factor Beta Receptor Binding I-SMAD Binding Actomyosin Structure Organization Z Disc SMAD Protein Signal Transduction DNA-templated Transcription R-SMAD Binding Embryonic Cranial Skeleton Morphogenesis Activin Receptor Signaling Pathway Endoderm Development MiRNA Processing RNA Polymerase II-specific DNA-binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity Ureteric Bud Development Negative Regulation Of Ossification Protein Stabilization Transcription Regulator Complex Gastrulation Mesonephric Epithelium Development Mesonephric Tubule Development Mesoderm Formation Nuclear Receptor Binding Nuclear Inner Membrane Myofibril Phosphatase Binding Protein Localization To T-tubule Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Positive Regulation Of Androgen Receptor Signaling Pathway NADP Phosphatase Activity NADPH Phosphatase Activity Formation Of Primary Germ Layer Embryonic Pattern Specification Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Osteoblast Differentiation
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