CH25H

Description		cholesterol 25-hydroxylase
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane
	Molecular Function	C-4 Methylsterol Oxidase Activity Cholesterol 25-hydroxylase Activity Monooxygenase Activity Iron Ion Binding Protein Binding Steroid Hydroxylase Activity Oxidoreductase Activity Metal Ion Binding
	Biological Process	Lipid Metabolic Process Steroid Biosynthetic Process Steroid Metabolic Process Cholesterol Metabolic Process Lipid Biosynthetic Process Sterol Biosynthetic Process Response To Type I Interferon B Cell Chemotaxis Negative Regulation Of Cholesterol Metabolic Process Negative Regulation Of Fusion Of Virus Membrane With Host Plasma Membrane
Pathways		Synthesis of bile acids and bile salts
Drugs
Diseases
GWAS		Atrioventricular conduction ( 21041692) Heart failure ( 20445134)
Interacting Genes		4 interacting genes: CCR4 GPR35 KRTAP12-4 OTX1
Entrez ID		9023
HPRD ID		05183
Ensembl ID		ENSG00000138135
Uniprot IDs		O95992
PDB IDs
Enriched GO Terms of Interacting Partners?		Chemokine Receptor Activity Chemokine-mediated Signaling Pathway Diencephalon Morphogenesis Positive Regulation Of Cytosolic Calcium Ion Concentration Metencephalon Development C-X-C Chemokine Receptor Activity Negative Regulation Of Voltage-gated Calcium Channel Activity Interneuron Migration G Protein-coupled Receptor Activity Cytokine-mediated Signaling Pathway Regulation Of Voltage-gated Calcium Channel Activity Tolerance Induction C-C Chemokine Binding C-C Chemokine Receptor Activity Negative Regulation Of Transporter Activity
Tagcloud ?