KIR2DL2 and CD93

Number of citations of the paper that reports this interaction (PMID 9476117)
16

Data Source:
HPRD (in vitro)

		KIR2DL2	CD93
Gene Name		killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2	CD93 molecule
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Plasma Membrane Cell Surface Integral Component Of Membrane Cytoplasmic Membrane-bounded Vesicle
	Molecular Function		Complement Component C1q Binding Receptor Activity Calcium Ion Binding Protein Binding Carbohydrate Binding
	Biological Process	Regulation Of Immune Response	Phagocytosis Viral Process Single Organismal Cell-cell Adhesion Macrophage Activation
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		2 interactors: CD93 HLA-C	23 interactors: ARHGAP15 BAG6 C1QA COL1A1 COL1A2 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COPS5 F12 FAM46A GIPC1 KIR2DL2 KNG1 MBL2 MSN MYD88 RANBP1 SCYL1 UBQLN2
Entrez ID		3803	22918
HPRD ID		16080	00396
Ensembl ID			ENSG00000125810
Uniprot IDs		P43627 Q6H2H0 Q8N742	Q9NPY3
PDB IDs		1EFX 2DL2 2DLI
Enriched GO Terms of Interacting Partners?		Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Viral Process Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Endogenous Antigen Macrophage Activation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Positive Regulation Of T Cell Mediated Cytotoxicity Regulation Of T Cell Mediated Cytotoxicity Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of T Cell Mediated Immunity Positive Regulation Of Cell Killing Regulation Of Leukocyte Mediated Cytotoxicity Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Immune System Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Response To Type I Interferon Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Interferon-gamma-mediated Signaling Pathway Positive Regulation Of Adaptive Immune Response Cellular Response To Interferon-gamma Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Response To Interferon-gamma Regulation Of Adaptive Immune Response Antigen Processing And Presentation Of Peptide Antigen Phagocytosis Antigen Processing And Presentation	Collagen Catabolic Process Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Extracellular Matrix Disassembly Extracellular Matrix Organization Extracellular Structure Organization Locomotion Movement Of Cell Or Subcellular Component Catabolic Process Protein Activation Cascade Axon Guidance Cellular Response To Amino Acid Stimulus Vesicle-mediated Transport Regulation Of Protein Processing Protein Heterotrimerization Axonogenesis Glomerular Basement Membrane Development Blood Coagulation, Intrinsic Pathway Regulation Of Blood Coagulation Response To External Stimulus Axon Development Response To Amino Acid Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Renal System Development Regulation Of Wound Healing Neuron Projection Morphogenesis Response To Stimulus Negative Regulation Of Proteolysis Endocytosis Receptor-mediated Endocytosis Negative Regulation Of Growth Of Symbiont In Host Negative Regulation Of Protein Processing Establishment Of Endothelial Barrier Urogenital System Development Cell Morphogenesis Involved In Differentiation Immune System Process Protein Trimerization Cellular Response To Acid Chemical Blood Coagulation Inflammatory Response Hemostasis Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Platelet Activation Neuron Projection Development Cell Projection Morphogenesis
Tagcloud ?		alleles analyse assigned c1 centromeric classical determination establish frequencies frequent genotype genotypes haplotypes hcv hla ifnl3 logic nsvr pegylated polymorphism powerful ppv predicting ribavirin rs12979860 sustained svr	29a 29b 29c acp5 calcitonin calcr cdc42 commitment concert cytoskeletal gpr85 gtpase hypothesize mir monocytic multinucleated nfia osteoclast osteoclastic osteoclasts raw264 rnas robo slit sponge srgap2 tartrate tempo transduced
Tagcloud (Difference) ?		alleles analyse assigned c1 centromeric classical determination establish frequencies frequent genotype genotypes haplotypes hcv hla ifnl3 logic nsvr pegylated polymorphism powerful ppv predicting ribavirin rs12979860 sustained svr	29a 29b 29c acp5 calcitonin calcr cdc42 commitment concert cytoskeletal gpr85 gtpase hypothesize mir monocytic multinucleated nfia osteoclast osteoclastic osteoclasts raw264 rnas robo slit sponge srgap2 tartrate tempo transduced
Tagcloud (Intersection) ?