KCNJ15 and KCNJ16

Number of citations of the paper that reports this interaction (PubMedID 9882736)
44

Data Source:
HPRD (in vitro, in vivo)

		KCNJ15	KCNJ16
Description		potassium inwardly rectifying channel subfamily J member 15	potassium inwardly rectifying channel subfamily J member 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Monoatomic Ion Channel Complex	Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Basolateral Plasma Membrane Monoatomic Ion Channel Complex
	Molecular Function	Inward Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding	Inward Rectifier Potassium Channel Activity
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Metal Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane	Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Potassium Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways		Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	Activation of G protein gated Potassium channels Potassium transport channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs		Ritodrine Yohimbine Butamben
Diseases
GWAS		A body shape index ( 34021172) Appendicular lean mass ( 33097823) Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Metabolite levels ( 23823483) Monocyte count ( 32888494) Non-response to antidepressants and depression ( 27622933) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Birth weight ( 31043758) Body mass index ( 26426971) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Metabolite levels ( 23823483) Palmitoleic acid (16:1n-7) levels ( 23362303) Periodontitis (DPAL) ( 24024966) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328) Serum metabolite levels ( 25569235) Thyrotoxic hypokalemic periodic paralysis ( 22863731) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		6 interacting genes: IL16 KCNJ16 KCNJ2 KCNJ5 PATJ SNTA1	4 interacting genes: KCNJ10 KCNJ15 KCNJ2 NEDD4
Entrez ID		3772	3773
HPRD ID		03659	16146
Ensembl ID		ENSG00000157551	ENSG00000153822
Uniprot IDs		Q99712	A8K434 Q8N538 Q9NPI9
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Monoatomic Ion Transport Membrane Repolarization During Action Potential Membrane Repolarization During Cardiac Muscle Cell Action Potential Voltage-gated Potassium Channel Complex Inward Rectifier Potassium Channel Activity Membrane Repolarization Regulation Of Heart Rate Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Membrane Repolarization Voltage-gated Potassium Channel Activity Involved In Cardiac Muscle Cell Action Potential Repolarization Cardiac Muscle Cell Action Potential Involved In Contraction Monoatomic Ion Channel Complex Regulation Of Heart Rate By Cardiac Conduction Cardiac Muscle Cell Action Potential Potassium Ion Import Across Plasma Membrane Potassium Ion Transmembrane Transport Cardiac Conduction Potassium Ion Transport Regulation Of Heart Contraction Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Ventricular Cardiac Muscle Cell Membrane Repolarization Regulation Of Blood Circulation Inorganic Cation Import Across Plasma Membrane Ventricular Cardiac Muscle Cell Action Potential Action Potential Metal Ion Transport Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Regulation Of Metal Ion Transport Positive Regulation Of Potassium Ion Transmembrane Transport Inorganic Ion Transmembrane Transport Import Across Plasma Membrane Positive Regulation Of Potassium Ion Transport Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Regulation Of Membrane Potential Kinesin Binding Regulation Of Skeletal Muscle Contraction Via Regulation Of Action Potential Ammon Gyrus Development Dendrite Morphogenesis Monoatomic Ion Transport Regulation Of System Process Post-embryonic Retina Morphogenesis In Camera-type Eye Netrin Receptor Binding Regulation Of Potassium Ion Transmembrane Transport Vestibular Nucleus Development Regulation Of Monoatomic Cation Transmembrane Transport Relaxation Of Skeletal Muscle	Inward Rectifier Potassium Channel Activity Regulation Of Monoatomic Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane Regulation Of Monoatomic Ion Transport Inorganic Cation Import Across Plasma Membrane Import Into Cell Metal Ion Transport Monoatomic Ion Channel Complex Import Across Plasma Membrane Potassium Ion Transmembrane Transport Regulation Of Resting Membrane Potential Monoatomic Cation Transport Potassium Ion Transport Monoatomic Ion Transport Potassium Ion Homeostasis Regulation Of Membrane Potential Regulation Of Transport Regulation Of Potassium Ion Transmembrane Transport Potassium Channel Activity Regulation Of Potassium Ion Transport Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Regulation Of Skeletal Muscle Contraction Via Regulation Of Action Potential Formation Of Structure Involved In A Symbiotic Process Inorganic Ion Transmembrane Transport Monoatomic Ion Transmembrane Transport Relaxation Of Skeletal Muscle Glutamate Reuptake Channel Inhibitor Activity Phosphothreonine Residue Binding Voltage-gated Potassium Channel Activity Involved In Cardiac Muscle Cell Action Potential Repolarization Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Transmembrane Transport Nuclear Receptor-mediated Corticosteroid Signaling Pathway Regulation Of Monoatomic Cation Transmembrane Transport ATP-activated Inward Rectifier Potassium Channel Activity Phosphoserine Residue Binding Beta-2 Adrenergic Receptor Binding Negative Regulation Of Potassium Ion Export Across Plasma Membrane Sodium Channel Inhibitor Activity Response To Metal Ion Potassium Channel Inhibitor Activity Regulation Of Metal Ion Transport L-glutamate Import Across Plasma Membrane Relaxation Of Cardiac Muscle Central Nervous System Myelination Astrocyte Projection Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Potassium Ion Export Across Plasma Membrane Progesterone Receptor Signaling Pathway
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