KCND2 and KCNIP2

Number of citations of the paper that reports this interaction (PMID 11287421)
55

Data Source:
HPRD (in vitro)

		KCND2	KCNIP2
Gene Name		potassium channel, voltage gated Shal related subfamily D, member 2	Kv channel interacting protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Intrinsic Component Of Plasma Membrane Dendritic Spine	Cytoplasm Voltage-gated Potassium Channel Complex
	Molecular Function	Voltage-gated Potassium Channel Activity A-type (transient Outward) Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Metal Ion Binding	A-type (transient Outward) Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity Identical Protein Binding Ion Channel Binding ER Retention Sequence Binding Protein N-terminus Binding
	Biological Process	Action Potential Synaptic Transmission Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport	Detection Of Calcium Ion Potassium Ion Transport Muscle Contraction Signal Transduction Synaptic Transmission Regulation Of Heart Contraction Clustering Of Voltage-gated Potassium Channels Potassium Ion Export Potassium Ion Transmembrane Transport Membrane Repolarization Regulation Of Cation Channel Activity
Pathways		Potassium Channels Voltage gated Potassium channels
Drugs
Diseases
GWAS		Alcohol and nictotine co-dependence ( 22488850) Immune reponse to smallpox (secreted IL-12p40) ( 22610502)
Protein-Protein Interactions		8 interactors: DLG4 DPP10 FLNC IL16 KCNIP1 KCNIP2 KCNIP4 NCS1	3 interactors: KCND2 KCND3 KCNIP1
Entrez ID		3751	30819
HPRD ID		09254	06880
Ensembl ID		ENSG00000184408	ENSG00000120049
Uniprot IDs		A4D0V9 Q75LS7 Q9NZV8	B3KSZ5 Q3YAC7 Q9NS61
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Ion Transmembrane Transport Regulation Of Ion Transport Detection Of Calcium Ion Potassium Ion Transmembrane Transport Potassium Ion Transport Metal Ion Transport Cation Transmembrane Transport Cation Transport Ion Transmembrane Transport Response To Calcium Ion Synaptic Transmission Regulation Of Ion Transmembrane Transporter Activity Clustering Of Voltage-gated Potassium Channels Regulation Of Transmembrane Transporter Activity Monovalent Inorganic Cation Transport Transmembrane Transport Regulation Of Behavior Ion Transport Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of Grooming Behavior Maintenance Of Apical/basal Cell Polarity Receptor Localization To Synapse Cell-cell Signaling Negative Regulation Of Receptor Internalization Positive Regulation Of Action Potential Locomotory Exploration Behavior Regulation Of Membrane Potential Potassium Ion Export Dendritic Spine Morphogenesis Neuronal Ion Channel Clustering Maintenance Of Cell Polarity Synaptic Vesicle Maturation Membrane Repolarization Vocalization Behavior Response To Metal Ion Induction Of Positive Chemotaxis Dendritic Spine Development Protein Localization To Synapse Negative Regulation Of Receptor-mediated Endocytosis Regulation Of Vesicle-mediated Transport Dendritic Spine Organization Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Detection Of Chemical Stimulus Cortical Actin Cytoskeleton Organization Exploration Behavior Postsynaptic Membrane Organization Establishment Or Maintenance Of Apical/basal Cell Polarity Cortical Cytoskeleton Organization Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Receptor Internalization	Potassium Ion Transmembrane Transport Potassium Ion Transport Regulation Of Ion Transmembrane Transport Synaptic Transmission Regulation Of Ion Transport Monovalent Inorganic Cation Transport Metal Ion Transport Cell-cell Signaling Cation Transmembrane Transport Cation Transport Ion Transmembrane Transport Protein Homooligomerization Regulation Of Membrane Potential Transmembrane Transport Ion Transport Protein Oligomerization Positive Regulation Of Action Potential Potassium Ion Export Detection Of Calcium Ion Membrane Repolarization Protein Complex Assembly Transport Action Potential Signaling Cell Communication Response To Calcium Ion Cellular Component Assembly Response To Metal Ion
Tagcloud ?		channel classes custom excitability gated genotyping gmm haplotype intriguing inwardly kcna1 kcnj3 kcnj6 kcnk9 latent member membership mild monthly pain persistent postsurgical potassium rectifying snps subfamily variations voltage warrant	ablate addressed apd arrhythmias arrhythmogenesis augmented beats caffeine cardiomyocytes cofactors establishment h3k4me h3k4me3 harbinger heritable inducibly initiating interacting isoproterenol kv marks methyltransferases pax premature ptip repolarization upstroke velocity ventricular
Tagcloud (Difference) ?		channel classes custom excitability gated genotyping gmm haplotype intriguing inwardly kcna1 kcnj3 kcnj6 kcnk9 latent member membership mild monthly pain persistent postsurgical potassium rectifying snps subfamily variations voltage warrant	ablate addressed apd arrhythmias arrhythmogenesis augmented beats caffeine cardiomyocytes cofactors establishment h3k4me h3k4me3 harbinger heritable inducibly initiating interacting isoproterenol kv marks methyltransferases pax premature ptip repolarization upstroke velocity ventricular
Tagcloud (Intersection) ?