KCND2 and KCNIP4

Number of citations of the paper that reports this interaction (PMID 11847232)
30

Data Source:
HPRD (in vivo)

		KCND2	KCNIP4
Gene Name		potassium channel, voltage gated Shal related subfamily D, member 2	Kv channel interacting protein 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Intrinsic Component Of Plasma Membrane Dendritic Spine	Plasma Membrane Dendrite Neuronal Cell Body
	Molecular Function	Voltage-gated Potassium Channel Activity A-type (transient Outward) Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Metal Ion Binding	Voltage-gated Ion Channel Activity Potassium Channel Activity Calcium Ion Binding
	Biological Process	Action Potential Synaptic Transmission Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport	Regulation Of Ion Transmembrane Transport Potassium Ion Transmembrane Transport
Pathways		Potassium Channels Voltage gated Potassium channels
Drugs
Diseases
GWAS		Alcohol and nictotine co-dependence ( 22488850) Immune reponse to smallpox (secreted IL-12p40) ( 22610502)	Obesity-related traits ( 23251661) Suicidal ideation ( 20877300)
Protein-Protein Interactions		8 interactors: DLG4 DPP10 FLNC IL16 KCNIP1 KCNIP2 KCNIP4 NCS1	4 interactors: APP KCND2 PSEN1 PSEN2
Entrez ID		3751	80333
HPRD ID		09254	12184
Ensembl ID		ENSG00000184408	ENSG00000185774
Uniprot IDs		A4D0V9 Q75LS7 Q9NZV8	A8K4N3 Q3YAB7 Q6PIL6
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Ion Transmembrane Transport Regulation Of Ion Transport Detection Of Calcium Ion Potassium Ion Transmembrane Transport Potassium Ion Transport Metal Ion Transport Cation Transmembrane Transport Cation Transport Ion Transmembrane Transport Response To Calcium Ion Synaptic Transmission Regulation Of Ion Transmembrane Transporter Activity Clustering Of Voltage-gated Potassium Channels Regulation Of Transmembrane Transporter Activity Monovalent Inorganic Cation Transport Transmembrane Transport Regulation Of Behavior Ion Transport Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of Grooming Behavior Maintenance Of Apical/basal Cell Polarity Receptor Localization To Synapse Cell-cell Signaling Negative Regulation Of Receptor Internalization Positive Regulation Of Action Potential Locomotory Exploration Behavior Regulation Of Membrane Potential Potassium Ion Export Dendritic Spine Morphogenesis Neuronal Ion Channel Clustering Maintenance Of Cell Polarity Synaptic Vesicle Maturation Membrane Repolarization Vocalization Behavior Response To Metal Ion Induction Of Positive Chemotaxis Dendritic Spine Development Protein Localization To Synapse Negative Regulation Of Receptor-mediated Endocytosis Regulation Of Vesicle-mediated Transport Dendritic Spine Organization Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Detection Of Chemical Stimulus Cortical Actin Cytoskeleton Organization Exploration Behavior Postsynaptic Membrane Organization Establishment Or Maintenance Of Apical/basal Cell Polarity Cortical Cytoskeleton Organization Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Receptor Internalization	Regulation Of Epidermal Growth Factor-activated Receptor Activity Endoplasmic Reticulum Calcium Ion Homeostasis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Protein Tyrosine Kinase Activity Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Receptor Activity Amyloid Precursor Protein Catabolic Process Notch Signaling Pathway Regulation Of Protein Binding Beta-amyloid Metabolic Process Amyloid Precursor Protein Metabolic Process Regulation Of Peptidyl-tyrosine Phosphorylation Membrane Protein Ectodomain Proteolysis Notch Receptor Processing Regulation Of Binding Learning Or Memory Cognition Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Dorsal/ventral Neural Tube Patterning Positive Regulation Of Coagulation Membrane Protein Proteolysis Brain Morphogenesis Regulation Of Cellular Amino Acid Metabolic Process Cellular Metal Ion Homeostasis Cellular Cation Homeostasis Forebrain Development Cellular Ion Homeostasis Single-organism Behavior Thymus Development Metal Ion Homeostasis Neuron Apoptotic Process Neural Tube Patterning Regulation Of Cellular Ketone Metabolic Process T Cell Activation Involved In Immune Response Neuron Death Cellular Chemical Homeostasis Ion Homeostasis Behavior Somitogenesis Cell Fate Specification Somite Development Cell Activation Cellular Homeostasis T Cell Receptor Signaling Pathway Regulation Of Protein Kinase Activity Myeloid Leukocyte Differentiation Segmentation Brain Development
Tagcloud ?		channel classes custom excitability gated genotyping gmm haplotype intriguing inwardly kcna1 kcnj3 kcnj6 kcnk9 latent member membership mild monthly pain persistent postsurgical potassium rectifying snps subfamily variations voltage warrant
Tagcloud (Difference) ?		channel classes custom excitability gated genotyping gmm haplotype intriguing inwardly kcna1 kcnj3 kcnj6 kcnk9 latent member membership mild monthly pain persistent postsurgical potassium rectifying snps subfamily variations voltage warrant
Tagcloud (Intersection) ?