KRT77 and KRT25

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		KRT77	KRT25
Description		keratin 77	keratin 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome	Cytoplasm Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis Protein Heterodimerization Activity
	Biological Process	Keratinization Intermediate Filament Organization	Morphogenesis Of An Epithelium Cytoskeleton Organization Epithelial Cell Differentiation Hair Follicle Morphogenesis Hair Cycle Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS			Asthma ( 30929738 31959851) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		12 interacting genes: KRT14 KRT15 KRT16 KRT19 KRT25 KRT27 KRT31 KRT33B KRT34 KRT35 KRT36 MDFI	26 interacting genes: HGS KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT73 KRT74 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT83 KRT85 KRT86 MORN4 PPL
Entrez ID		374454	147183
HPRD ID		13934	17242
Ensembl ID		ENSG00000189182	ENSG00000204897
Uniprot IDs		Q0IIN1 Q7Z794	Q6ZPD6 Q7Z3Z0
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Supramolecular Fiber Organization Anatomical Structure Morphogenesis Cytoskeleton Organization Cytoskeleton Cell Differentiation Hair Cycle Cellular Developmental Process Structural Constituent Of Cytoskeleton Organelle Organization Epidermis Development Extracellular Exosome Developmental Process Cytosol Tissue Development Cell Differentiation Involved In Embryonic Placenta Development Hair Follicle Morphogenesis Cornified Envelope Keratinocyte Differentiation Hair Cycle Process Cell Periphery Epidermal Cell Differentiation Terminal Web Keratin Filament Binding Keratinocyte Migration Intermediate Filament Bundle Assembly Dorsal/ventral Axis Specification Trophoblast Giant Cell Differentiation Costamere Basal Part Of Cell Dystrophin-associated Glycoprotein Complex	Keratinization Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Intermediate Filament Organization Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Extracellular Exosome Cytosol Cornified Envelope Epidermis Development Structural Constituent Of Cytoskeleton Intermediate Filament Cytoskeleton Tissue Development Peptide Cross-linking Desmosome Intermediate Filament Polymerization Protein Binding Structural Molecule Activity Keratinocyte Activation Intermediate Filament Polymerization Or Depolymerization Negative Regulation Of Entry Of Bacterium Into Host Cell Response To Wounding
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