KRT25 and KRT80

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		KRT25	KRT80
Description		keratin 25	keratin 80
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome	Cytoplasm Cytosol Intermediate Filament Desmosome Keratin Filament Intermediate Filament Cytoskeleton
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis Protein Heterodimerization Activity	Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Morphogenesis Of An Epithelium Cytoskeleton Organization Epithelial Cell Differentiation Hair Follicle Morphogenesis Hair Cycle Intermediate Filament Organization	Keratinization Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Asthma ( 30929738 31959851) Cognitive decline rate in late mild cognitive impairment ( 26252872)	Cutaneous leishmaniasis ( 32830257) Diisocyanate-induced asthma ( 25918132) Telomere length ( 24465473)
Interacting Genes		26 interacting genes: HGS KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT73 KRT74 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT83 KRT85 KRT86 MORN4 PPL	22 interacting genes: AIRIM COPS3 GINS3 KRT14 KRT15 KRT16 KRT19 KRT20 KRT24 KRT25 KRT28 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT38 LCA5L LMO2 MEOX2 UCHL5
Entrez ID		147183	144501
HPRD ID		17242	14068
Ensembl ID		ENSG00000204897	ENSG00000167767
Uniprot IDs		Q6ZPD6 Q7Z3Z0	Q6KB66
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratinization Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Intermediate Filament Organization Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Extracellular Exosome Cytosol Cornified Envelope Epidermis Development Structural Constituent Of Cytoskeleton Intermediate Filament Cytoskeleton Tissue Development Peptide Cross-linking Desmosome Intermediate Filament Polymerization Protein Binding Structural Molecule Activity Keratinocyte Activation Intermediate Filament Polymerization Or Depolymerization Negative Regulation Of Entry Of Bacterium Into Host Cell Response To Wounding	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Morphogenesis Of An Epithelium Supramolecular Fiber Organization Epithelial Cell Differentiation Tissue Morphogenesis Cytoskeleton Organization Anatomical Structure Morphogenesis Cytoskeleton Organelle Organization Hair Cycle Structural Constituent Of Cytoskeleton Cell Differentiation Epidermis Development Extracellular Exosome Cellular Developmental Process Cytosol Developmental Process Tissue Development Hair Follicle Morphogenesis Intermediate Filament Cytoskeleton Cornified Envelope Keratinocyte Differentiation Protein Binding Keratinization Terminal Web Hair Cycle Process
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