KRT25 and KRT81

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		KRT25	KRT81
Description		keratin 25	keratin 81
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome	Extracellular Space Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis Protein Heterodimerization Activity	Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Morphogenesis Of An Epithelium Cytoskeleton Organization Epithelial Cell Differentiation Hair Follicle Morphogenesis Hair Cycle Intermediate Filament Organization	Keratinization Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs
Diseases			Monilethrix
GWAS		Asthma ( 30929738 31959851) Cognitive decline rate in late mild cognitive impairment ( 26252872)	Diisocyanate-induced asthma ( 25918132)
Interacting Genes		26 interacting genes: HGS KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT73 KRT74 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT83 KRT85 KRT86 MORN4 PPL	30 interacting genes: CYSRT1 DMRTB1 HOXA1 KRT13 KRT14 KRT15 KRT16 KRT18 KRT19 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KXD1 LCA5L MEOX2 OIP5 OTX1 PCBP3 SKIL
Entrez ID		147183	3887
HPRD ID		17242	03691
Ensembl ID		ENSG00000204897	ENSG00000205426
Uniprot IDs		Q6ZPD6 Q7Z3Z0	Q14533
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratinization Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Intermediate Filament Organization Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Extracellular Exosome Cytosol Cornified Envelope Epidermis Development Structural Constituent Of Cytoskeleton Intermediate Filament Cytoskeleton Tissue Development Peptide Cross-linking Desmosome Intermediate Filament Polymerization Protein Binding Structural Molecule Activity Keratinocyte Activation Intermediate Filament Polymerization Or Depolymerization Negative Regulation Of Entry Of Bacterium Into Host Cell Response To Wounding	Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Intermediate Filament Structural Molecule Activity Epithelial Cell Differentiation Morphogenesis Of An Epithelium Tissue Morphogenesis Supramolecular Fiber Organization Cytoskeleton Organization Anatomical Structure Morphogenesis Cytoskeleton Extracellular Exosome Cell Differentiation Developmental Process Organelle Organization Cellular Developmental Process Hair Cycle Epidermis Development Structural Constituent Of Cytoskeleton Cytosol Hair Follicle Morphogenesis Tissue Development Cornified Envelope Hair Cycle Process Cell Periphery Protein Binding Semicircular Canal Formation Diencephalon Morphogenesis C-rich Single-stranded DNA Binding Establishment Of Skin Barrier Skin Epidermis Development Abducens Nerve Formation Optokinetic Behavior Intermediate Filament Cytoskeleton
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