ENO2 and ANXA11

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ENO2	ANXA11
Gene Name		enolase 2 (gamma, neuronal)	annexin A11
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Phosphopyruvate Hydratase Complex Photoreceptor Inner Segment Extracellular Space Cytosol Plasma Membrane Perikaryon Extracellular Vesicular Exosome	Nuclear Envelope Nucleoplasm Cytoplasm Spindle Membrane Midbody Melanosome Specific Granule Azurophil Granule Phagocytic Vesicle Extracellular Vesicular Exosome
	Molecular Function	Magnesium Ion Binding Phosphopyruvate Hydratase Activity	Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Phosphatidylethanolamine Binding MHC Class II Protein Complex Binding S100 Protein Binding Poly(A) RNA Binding Calcium-dependent Protein Binding
	Biological Process	Carbohydrate Metabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Pathogenesis Small Molecule Metabolic Process	Phagocytosis Cytokinesis, Completion Of Separation Response To Calcium Ion
Pathways		Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Sarcoidosis ( 22936702)
Protein-Protein Interactions		23 interactors: A2M ACD ANXA11 C16orf45 C6orf47 ENSA EXOC5 HABP4 HK1 HSF1 IL17B MAP4 NAT9 NDUFS7 POT1 SIGIRR SNUPN ST3GAL2 SUMO4 TERF1 TINF2 TUBA4A UBE2C	10 interactors: ALG2 CEP55 ENO2 HNRNPH3 PDCD6 PLSCR1 S100A6 SRI TFG ZDHHC17
Entrez ID		2026	311
HPRD ID		00573	03983
Ensembl ID		ENSG00000111674	ENSG00000122359
Uniprot IDs		P09104 Q6FHV6	B4DVE7 P50995 Q5T0G8
PDB IDs		1TE6 2AKM 2AKZ 3UCC 3UCD 3UJE 3UJF 3UJR 3UJS
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Telomere Assembly Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Replication Regulation Of Telomerase Activity Telomere Maintenance Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Telomere Maintenance Via Telomere Lengthening Regulation Of DNA Replication Regulation Of DNA Biosynthetic Process Protein Localization To Chromosome, Telomeric Region Telomere Capping Positive Regulation Of Telomerase Activity Mitotic Cell Cycle Process Organelle Organization Cell Division Telomere Maintenance Via Telomerase Negative Regulation Of Telomerase Activity Platelet Degranulation Mitotic Cell Cycle Positive Regulation Of Telomere Maintenance Regulation Of Organelle Organization Cell Cycle Positive Regulation Of DNA Biosynthetic Process Cellular Component Assembly G2/M Transition Of Mitotic Cell Cycle RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Exocytosis Cell Cycle Process Positive Regulation Of DNA Metabolic Process Protein Localization To Chromosome Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Organelle Organization Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Negative Regulation Of Catalytic Activity Mitotic Spindle Checkpoint Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Chromosome Segregation Platelet Activation Cellular Localization Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Negative Regulation Of Protein ADP-ribosylation	Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of TOR Signaling Negative Regulation Of Protein Kinase B Signaling Positive Regulation Of Endothelial Cell Migration Regulation Of TOR Signaling Positive Regulation Of Endothelial Cell Proliferation Cellular Response To Heat Protein Glycosylation In Endoplasmic Reticulum Positive Regulation Of Epithelial Cell Migration Regulation Of Endothelial Cell Proliferation Protein Localization Regulation Of Signaling Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Vascular Endothelial Growth Factor Receptor Signaling Pathway Intracellular Sequestering Of Iron Ion Zymogen Activation Regulation Of Endothelial Cell Migration Negative Regulation Of Cellular Response To Growth Factor Stimulus Response To Heat Response To Calcium Ion Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Protein Kinase B Signaling Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Positive Regulation Of Angiogenesis Positive Regulation Of Endopeptidase Activity Regulation Of Epithelial Cell Migration Positive Regulation Of Peptidase Activity Positive Regulation Of Epithelial Cell Proliferation Establishment Of Protein Localization Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Phosphatidylserine Biosynthetic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Cellular Component Movement Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of High Voltage-gated Calcium Channel Activity Response To Temperature Stimulus Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Signal Transduction Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Relaxation Of Muscle Regulation Of Angiogenesis Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Cell Proliferation Regulation Of Intracellular Signal Transduction Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Tagcloud ?		begin differentially dige enolase failures gondii gra7 hypothetical imc1 mic2 naturally parasite proteomics pyrimethamine qrt rh rhoptry rop2 rop2a spectrometer spots strains sulfadiazine sulfonamide tga tgh toxoplasma toxoplasmosis undertook	alg apparatus architectural associates cage cargo cargoes coat coordinating copii ef eres exit golgi juxtanuclear maintains penta periphery physically scattering sec31a secretory specialized stabilize synchronous trafficking vesicle vesicular
Tagcloud (Difference) ?		begin differentially dige enolase failures gondii gra7 hypothetical imc1 mic2 naturally parasite proteomics pyrimethamine qrt rh rhoptry rop2 rop2a spectrometer spots strains sulfadiazine sulfonamide tga tgh toxoplasma toxoplasmosis undertook	alg apparatus architectural associates cage cargo cargoes coat coordinating copii ef eres exit golgi juxtanuclear maintains penta periphery physically scattering sec31a secretory specialized stabilize synchronous trafficking vesicle vesicular
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