ACADVL and RPSA

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ACADVL	RPSA
Gene Name		acyl-CoA dehydrogenase, very long chain	ribosomal protein SA
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Mitochondrial Nucleoid	Nucleus Cytoplasm Cytosol Plasma Membrane Membrane Cytosolic Small Ribosomal Subunit 90S Preribosome Extracellular Vesicular Exosome
	Molecular Function	Acyl-CoA Dehydrogenase Activity Long-chain-acyl-CoA Dehydrogenase Activity Flavin Adenine Dinucleotide Binding	Structural Constituent Of Ribosome Laminin Receptor Activity Protein Binding Ribosome Binding Laminin Binding Poly(A) RNA Binding
	Biological Process	Temperature Homeostasis Fatty Acid Beta-oxidation Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Energy Derivation By Oxidation Of Organic Compounds Epithelial Cell Differentiation Endoplasmic Reticulum Unfolded Protein Response Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase Cellular Lipid Metabolic Process Cellular Protein Metabolic Process Small Molecule Metabolic Process Negative Regulation Of Fatty Acid Biosynthetic Process Negative Regulation Of Fatty Acid Oxidation Regulation Of Cholesterol Metabolic Process	Ribosomal Small Subunit Assembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Export From Nucleus Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Cell Adhesion Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways		Fatty acid, triacylglycerol, and ketone body metabolism IRE1alpha activates chaperones Metabolism of lipids and lipoproteins Mitochondrial Fatty Acid Beta-Oxidation mitochondrial fatty acid beta-oxidation of saturated fatty acids XBP1(S) activates chaperone genes Beta oxidation of palmitoyl-CoA to myristoyl-CoA Unfolded Protein Response (UPR)	Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: GPHN RPSA SOCS3	27 interactors: ABCD1 ACADVL ACD ANKH C6orf106 CALM2 CBX5 CLEC4G CSF2RA DCTN6 GNMT HBG2 HNRNPD IL7R ITGA6 KARS LAMA2 NKX3-1 POT1 PRND PROS1 RNF114 RPS21 SLC2A5 SUMO4 TINF2 TRIB3
Entrez ID		37	3921
HPRD ID		01940	01038
Ensembl ID		ENSG00000072778	ENSG00000168028
Uniprot IDs		B3KPA6 P49748	P08865
PDB IDs		2UXW 3B96	3BCH 3J3A
Enriched GO Terms of Interacting Partners?		Glycine Receptor Clustering Molybdenum Incorporation Into Molybdenum-molybdopterin Complex RRNA Export From Nucleus Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Establishment Of Synaptic Specificity At Neuromuscular Junction Spongiotrophoblast Differentiation Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Transport RRNA 3'-end Processing Protein Localization To Membrane Molybdopterin Cofactor Biosynthetic Process Molybdopterin Cofactor Metabolic Process Mo-molybdopterin Cofactor Biosynthetic Process Ribosomal Small Subunit Assembly Branching Involved In Labyrinthine Layer Morphogenesis Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of 5.8S RRNA Spongiotrophoblast Layer Development Trophoblast Giant Cell Differentiation Regulation Of Interferon-gamma-mediated Signaling Pathway JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Regulation Of Response To Interferon-gamma Negative Regulation Of JAK-STAT Cascade Labyrinthine Layer Morphogenesis Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus Postsynaptic Membrane Organization Embryonic Placenta Morphogenesis Ribosome Assembly Maturation Of SSU-rRNA Membrane Organization Cell Differentiation Involved In Embryonic Placenta Development Placenta Blood Vessel Development Negative Regulation Of Insulin Receptor Signaling Pathway Ribosomal Small Subunit Biogenesis Response To Growth Hormone Regulation Of Type I Interferon-mediated Signaling Pathway Cellular Protein Metabolic Process Receptor Clustering Neuromuscular Junction Development JAK-STAT Cascade Labyrinthine Layer Development Regulation Of Insulin Receptor Signaling Pathway RNA Phosphodiester Bond Hydrolysis, Endonucleolytic RNA Export From Nucleus Cellular Protein Localization Synapse Assembly Regulation Of Cellular Response To Insulin Stimulus Water-soluble Vitamin Metabolic Process	Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Protein Localization To Chromosome, Telomeric Region Telomere Capping Negative Regulation Of DNA Replication Positive Regulation Of Telomerase Activity Positive Regulation Of Transferase Activity Telomere Maintenance Positive Regulation Of Telomere Maintenance Negative Regulation Of Fatty Acid Biosynthetic Process Blood Coagulation Hemostasis Negative Regulation Of Chromosome Organization Regulation Of Telomerase Activity Negative Regulation Of DNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of DNA Biosynthetic Process Negative Regulation Of Fatty Acid Metabolic Process Regulation Of Body Fluid Levels Regulation Of DNA Replication Wound Healing Negative Regulation Of Biosynthetic Process Protein Localization To Chromosome Positive Regulation Of DNA Metabolic Process Cellular Response To Organic Substance Telomere Maintenance Via Telomere Lengthening Regulation Of Fatty Acid Biosynthetic Process Response To Wounding Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Lipid Biosynthetic Process Negative Regulation Of Protein ADP-ribosylation Lysyl-tRNA Aminoacylation Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Peroxisomal Long-chain Fatty Acid Import Fructose Transport Regulation Of DNA Biosynthetic Process Fatty Acid Beta-oxidation Regulation Of Chromosome Organization Regulation Of Cellular Ketone Metabolic Process Positive Regulation Of Metabolic Process Glycogen Metabolic Process Response To Stress Regulation Of Protein ADP-ribosylation Inorganic Diphosphate Transport Positive Regulation Of Androgen Secretion Interleukin-7-mediated Signaling Pathway
Tagcloud ?		2t 390del 7123997t acyl boy coa decompensation deterioration diagnose downhill glu130del hong illustrates inborn kong lives newborn obviated opportunity prompt save siblings succumbed sudden tandem treatable unexpected urge vlcad	abolish arg357 bonds confer conformational crystal elusive exhibits exquisite hydrogen hydrophobic insights lys303 mode mtb phe307 phe310 poa pyrazinamide pyrazinoic pza questions reveals ribosomal s1 shortening tb terminus tmrna
Tagcloud (Difference) ?		2t 390del 7123997t acyl boy coa decompensation deterioration diagnose downhill glu130del hong illustrates inborn kong lives newborn obviated opportunity prompt save siblings succumbed sudden tandem treatable unexpected urge vlcad	abolish arg357 bonds confer conformational crystal elusive exhibits exquisite hydrogen hydrophobic insights lys303 mode mtb phe307 phe310 poa pyrazinamide pyrazinoic pza questions reveals ribosomal s1 shortening tb terminus tmrna
Tagcloud (Intersection) ?