H19 and PPP1R3E

Number of citations of the paper that reports this interaction (PubMedID 37298108)
45

Data Source:
BioGRID (unspecified method)

		H19	PPP1R3E
Description		H19 imprinted maternally expressed transcript	protein phosphatase 1 regulatory subunit 3E
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Protein Phosphatase Type 1 Complex Glycogen Granule
	Molecular Function		Phosphoprotein Phosphatase Activity Protein Phosphatase 1 Binding [phosphorylase] Phosphatase Activity Glycogen Binding
	Biological Process		Glycogen Metabolic Process Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Glycogen Biosynthetic Process
Pathways
Drugs
Diseases		Russell-Silver syndrome; Silver-Russell syndrome Beckwith-Wiedemann syndrome
GWAS		Celiac disease ( 23936387) Creatinine levels ( 29403010) Diastolic blood pressure ( 27841878) Diastolic blood pressure (cigarette smoking interaction) ( 29455858) DNA methylation (parent-of-origin) ( 23725790) DNA methylation (variation) ( 23725790) Estimated glomerular filtration rate ( 30604766) Glomerular filtration rate ( 29403010) Hypertension ( 30487518) Pulse pressure ( 27841878) Squamous cell lung carcinoma ( 28604730) Systolic blood pressure ( 27841878 28135244) Systolic blood pressure (cigarette smoking interaction) ( 29455858)	Pulse pressure ( 27841878) Serum alkaline phosphatase levels ( 33547301) Systolic blood pressure ( 27841878)
Interacting Genes		21 interacting genes: BCLAF1 DDX5 DSP ESRP1 FMR1 IFIT5 ILF2 MYO1D NSD2 PCCA PCCB PPP1R3E PRKRA SERBP1 SRSF10 SRSF8 SRSF9 SSB STON2 TPM1 U2SURP	2 interacting genes: H19 PPP1CA
Entrez ID		283120	90673
HPRD ID
Ensembl ID		ENSG00000130600	ENSG00000235194
Uniprot IDs			Q9H7J1
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Binding Regulation Of RNA Splicing Nucleic Acid Binding Regulation Of MRNA Splicing, Via Spliceosome RNA Processing Regulation Of MRNA Processing Propionyl-CoA Carboxylase Activity Regulation Of MRNA Metabolic Process Poly(U) RNA Binding RNA Splicing MRNA Metabolic Process MRNA Processing Short-chain Fatty Acid Catabolic Process Ribonucleoprotein Complex SiRNA Binding Sequence-specific MRNA Binding Nuclear Speck Translation Repressor Activity Short-chain Fatty Acid Metabolic Process Nuclear-transcribed MRNA Catabolic Process Negative Regulation Of Gene Expression Regulation Of Viral Life Cycle Catalytic Complex Negative Regulation Of MRNA Splicing, Via Spliceosome Branched-chain Amino Acid Metabolic Process MRNA Catabolic Process Negative Regulation Of RNA Splicing MRNA 3'-UTR Binding Regulation Of Viral Process Negative Regulation Of Macromolecule Biosynthetic Process Nucleolus MRNA Splice Site Recognition MiRNA Processing Negative Regulation Of Biosynthetic Process RNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process MiRNA Transcription Positive Regulation Of Intracellular Transport Of Viral Material Ligase Activity, Forming Carbon-carbon Bonds Nuclear Histone MRNA Catabolic Process Positive Regulation Of Heart Rate By Epinephrine Regulation Of Inner Ear Auditory Receptor Cell Fate Specification Ventricular Cardiac Muscle Tissue Morphogenesis Regulation Of Primary Metabolic Process RNA Catabolic Process Nucleic Acid Metabolic Process Protein-RNA Complex Assembly Negative Regulation Of Macromolecule Metabolic Process	RNA Polymerase II Promoter Clearance Regulation Of Glycogen Catabolic Process Positive Regulation Of Termination Of DNA-templated Transcription Glycogen Granule Regulation Of Translational Initiation In Response To Stress Positive Regulation Of Termination Of RNA Polymerase II Transcription PTW/PP1 Phosphatase Complex Double-strand Break Repair Via Alternative Nonhomologous End Joining RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled Telomere Maintenance In Response To DNA Damage Protein Phosphatase Type 1 Complex Transition Metal Ion Binding Cadherin Binding Involved In Cell-cell Adhesion Positive Regulation Of Glycogen Biosynthetic Process Response To Lead Ion Entrainment Of Circadian Clock By Photoperiod Regulation Of Translation In Response To Stress Negative Regulation Of Transcription Elongation By RNA Polymerase II Protein Phosphatase 1 Binding Negative Regulation Of DNA-templated Transcription, Elongation Photoperiodism Entrainment Of Circadian Clock Regulation Of Glycogen Biosynthetic Process Ribonucleoprotein Complex Binding Positive Regulation Of Protein-containing Complex Disassembly Regulation Of Glycogen Metabolic Process Positive Regulation Of Glucose Metabolic Process Transcription Elongation By RNA Polymerase II Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand DNA-templated Transcription Elongation Glycogen Metabolic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Double-strand Break Repair Via Nonhomologous End Joining Positive Regulation Of Transcription Elongation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Carbohydrate Catabolic Process Circadian Regulation Of Gene Expression Energy Reserve Metabolic Process Polysaccharide Metabolic Process Phosphatase Activity Protein Dephosphorylation Protein Serine/threonine Phosphatase Activity Regulation Of Transcription Elongation By RNA Polymerase II Telomere Maintenance Regulation Of Glucose Metabolic Process Lung Development Regulation Of DNA-templated Transcription Elongation Regulation Of Translational Initiation
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