IL15RA and RCVRN

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		IL15RA	RCVRN
Description		interleukin 15 receptor subunit alpha	recoverin
Image
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Nucleus Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Plasma Membrane Cell Surface Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Nuclear Membrane	Photoreceptor Outer Segment Photoreceptor Inner Segment Membrane Dendrite Cell Projection Perikaryon
	Molecular Function	Cytokine Receptor Activity Protein Binding Protein Kinase Binding Interleukin-15 Receptor Activity	Calcium Ion Binding Calcium Sensitive Guanylate Cyclase Activator Activity Metal Ion Binding
	Biological Process	Natural Killer Cell Differentiation Cell Surface Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Neuron Projection Development Response To Nutrient Levels Positive Regulation Of Natural Killer Cell Differentiation Interleukin-15-mediated Signaling Pathway Positive Regulation Of Phagocytosis	Signal Transduction Visual Perception Phototransduction Regulation Of Signal Transduction Regulation Of Calcium Ion Transport
Pathways		Interleukin-15 signaling Interleukin-15 signaling	Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade
Drugs			Myristic acid
Diseases
GWAS		Alopecia areata ( 25608926) Asthma ( 31619474 31959851) Asthma (bronchodilator response) ( 23508266) Atopic dermatitis ( 26482879) Blood protein levels ( 30072576) Diisocyanate-induced asthma ( 25918132) Inflammatory bowel disease ( 23128233) Medication use (thyroid preparations) ( 31015401) Neuroblastoma (pediatric) ( 32599975) Soluble interleukin-2 receptor subunit alpha ( 26293465)
Interacting Genes		12 interacting genes: AXL BCL10 CASK CDK2 CDK4 IL15 IL2RB IL2RG PIAS4 RCVRN SYK TRAF2	11 interacting genes: CAV1 GIT2 GRK1 GRK2 GRK5 GRK6 IL15RA PQBP1 SMAD3 TGFBR2 TOP1
Entrez ID		3601	5957
HPRD ID		03045	01558
Ensembl ID		ENSG00000134470	ENSG00000109047
Uniprot IDs		A0A0A0MS77 G8CVM3 Q13261	P35243
PDB IDs		2ERS 2Z3Q 2Z3R 4GS7	2D8N
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Endocytosis Interleukin-15-mediated Signaling Pathway Regulation Of Production Of Molecular Mediator Of Immune Response Regulation Of Cytokine Production Involved In Immune Response Regulation Of Endocytosis Regulation Of Vesicle-mediated Transport Interleukin-15 Receptor Activity Interleukin-2 Binding Interleukin-2 Receptor Activity Regulation Of Phagocytosis Positive Regulation Of Lymphocyte Activation Positive Regulation Of Lymphocyte Differentiation Signal Transduction Immune Response Positive Regulation Of Cell Activation Positive Regulation Of Mast Cell Cytokine Production Regulation Of Cytokine-mediated Signaling Pathway Cytokine-mediated Signaling Pathway Positive Regulation Of Leukocyte Differentiation Positive Regulation Of Transport Lymphocyte Activation Cell Surface Receptor Signaling Pathway Regulation Of Lymphocyte Differentiation Cellular Response To Oxygen-containing Compound Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Protein Kinase Activity Regulation Of Lymphocyte Activation Positive Regulation Of Phagocytosis Lymphocyte Differentiation Positive Regulation Of Natural Killer Cell Differentiation Leukocyte Activation Positive Regulation Of T Cell Activation Positive Regulation Of Immune System Process Regulation Of Transport Interleukin-2-mediated Signaling Pathway Positive Regulation Of Immune Effector Process Positive Regulation Of Cytokine Production Involved In Immune Response Positive Regulation Of Leukocyte Cell-cell Adhesion Kinase Activity Regulation Of Natural Killer Cell Differentiation T Cell Activation Regulation Of Cell Activation Positive Regulation Of Cellular Component Organization Cell Activation Transferase Activity Cellular Response To Nitric Oxide Mononuclear Cell Differentiation Cellular Response To Reactive Nitrogen Species Positive Regulation Of Cell-cell Adhesion Positive Regulation Of B Cell Differentiation	G Protein-coupled Receptor Kinase Activity Beta-adrenergic Receptor Kinase Activity Regulation Of G Protein-coupled Receptor Signaling Pathway Protein Serine/threonine Kinase Activity Gastrulation Regulation Of The Force Of Heart Contraction By Chemical Signal Tachykinin Receptor Signaling Pathway Protein Kinase Activity Animal Organ Development Regulation Of Signal Transduction Kinase Activity Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Communication Regulation Of Signaling Double-stranded DNA Binding G Protein-coupled Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway SMAD Protein Signal Transduction Release Of Cytochrome C From Mitochondria RRNA Transcription Regulation Of The Force Of Heart Contraction ATP Binding Embryonic Cranial Skeleton Morphogenesis Activin Receptor Signaling Pathway Negative Regulation Of Fibroblast Proliferation Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Death Programmed Cell Death Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Programmed Necrotic Cell Death Signal Transduction Fibroblast Proliferation Positive Regulation Of SMAD Protein Signal Transduction Negative Regulation Of Relaxation Of Smooth Muscle Regulation Of Muscle System Process Negative Regulation Of The Force Of Heart Contraction By Chemical Signal Inward Rectifier Potassium Channel Inhibitor Activity Leukocyte Activation Somitogenesis Segmentation Negative Regulation Of Lung Blood Pressure In Utero Embryonic Development Positive Regulation Of MiRNA Transcription Chordate Embryonic Development Nuclear Mineralocorticoid Receptor Binding Transcription Coactivator Binding Cell Proliferation Involved In Endocardial Cushion Morphogenesis Positive Regulation Of Tolerance Induction To Self Antigen Superior Endocardial Cushion Morphogenesis
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