IL11RA and IL11

Number of citations of the paper that reports this interaction (PubMedID 7670098)
0

Data Source:
HPRD (in vivo, in vitro)

		IL11RA	IL11
Description		interleukin 11 receptor subunit alpha	interleukin 11
Image
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Membrane Receptor Complex	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	Transmembrane Signaling Receptor Activity Cytokine Receptor Activity Interleukin-11 Receptor Activity Protein Binding Interleukin-11 Binding	Cytokine Activity Interleukin-11 Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	Embryo Implantation Positive Regulation Of Cell Population Proliferation Cytokine-mediated Signaling Pathway Cell Differentiation Developmental Process Interleukin-11-mediated Signaling Pathway Head Development	Cell Population Proliferation Positive Regulation Of Cell Population Proliferation B Cell Differentiation Megakaryocyte Differentiation Positive Regulation Of Peptidyl-serine Phosphorylation Interleukin-11-mediated Signaling Pathway Positive Regulation Of MAPK Cascade Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Hormone Secretion Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Complement-dependent Cytotoxicity Negative Regulation Of Endothelial Cell Apoptotic Process
Pathways		IL-6-type cytokine receptor ligand interactions	IL-6-type cytokine receptor ligand interactions
Drugs		Oprelvekin
Diseases
GWAS		CTACK levels ( 27989323)	Appendicular lean mass ( 33097823) Osteoarthritis (hip) ( 30374069) Response to antidepressants ( 20360315)
Interacting Genes		3 interacting genes: IL11 OLFM4 USP40	7 interacting genes: IL11RA MAGEA11 S100A1 S100A6 S100B S100P UBQLN2
Entrez ID		3590	3589
HPRD ID		02965	00980
Ensembl ID		ENSG00000137070	ENSG00000095752
Uniprot IDs		Q14626	A8K3F7 P20809
PDB IDs		6O4P 8DPS 8DPT 8DPU 8QY4	4MHL 6O4O 8DPS 8DPT 8DPU 8DPV 8DPW 8QY4
Enriched GO Terms of Interacting Partners?		Interleukin-11 Receptor Binding Dendritic Cell Dendrite Assembly Positive Regulation Of Myeloid Dendritic Cell Chemotaxis Mesangial Cell-matrix Adhesion CCR7 Chemokine Receptor Binding CCL21-activated CCR7 Signaling Pathway Positive Regulation Of Cell-substrate Adhesion Negative Regulation Of Dendritic Cell Dendrite Assembly Regulation Of Dendritic Cell Dendrite Assembly Negative Regulation Of Leukocyte Tethering Or Rolling Chemokine (C-C Motif) Ligand 21 Signaling Pathway Cytokine Activity Positive Regulation Of Phospholipase C/protein Kinase C Signal Transduction Regulation Of Cell-substrate Adhesion Interleukin-11-mediated Signaling Pathway Megakaryocyte Differentiation Regulation Of Complement-dependent Cytotoxicity Regulation Of Dendritic Cell Chemotaxis Positive Regulation Of Pseudopodium Assembly Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Positive Regulation Of Dendritic Cell Antigen Processing And Presentation Immunological Synapse Formation Positive Regulation Of Dendritic Cell Chemotaxis Negative Regulation Of Dendritic Cell Apoptotic Process Positive Regulation Of T Cell Chemotaxis Regulation Of Canonical NF-kappaB Signal Transduction Chemokine Receptor Binding Establishment Of T Cell Polarity Negative Regulation Of Cellular Extravasation Azurophil Granule Specific Granule Regulation Of Leukocyte Tethering Or Rolling Regulation Of T Cell Chemotaxis Cellular Response To Chemokine Dendritic Cell Chemotaxis Cytokine-mediated Signaling Pathway Extracellular Space Positive Regulation Of Lymphocyte Chemotaxis Positive Regulation Of Glycoprotein Biosynthetic Process Cellular Response To Prostaglandin E Stimulus Positive Regulation Of Glycoprotein Metabolic Process Eosinophil Chemotaxis Eosinophil Migration Positive Regulation Of MAPK Cascade Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Antigen Processing And Presentation Dendritic Cell Migration Positive Regulation Of Neutrophil Chemotaxis Positive Regulation Of Cell Adhesion Mediated By Integrin Regulation Of Lymphocyte Chemotaxis	Calcium-dependent Protein Binding S100 Protein Binding Calcium Ion Binding Protein Homodimerization Activity Identical Protein Binding Extracellular Region Ruffle Negative Regulation Of G Protein-coupled Receptor Internalization Interleukin-11 Receptor Activity Interleukin-11 Binding Axonogenesis Negative Regulation Of Clathrin-dependent Endocytosis Response To Anesthetic Response To Methylmercury Sympathetic Neuron Projection Extension Interleukin-11-mediated Signaling Pathway Negative Regulation Of Skeletal Muscle Cell Differentiation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?