RILPL1 and PIP4P1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RILPL1	PIP4P1
Description		Rab interacting lysosomal protein like 1	phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Plasma Membrane Cilium Ciliary Basal Body Cell Projection	Nucleoplasm Lysosome Lysosomal Membrane Endosome Plasma Membrane Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Late Endosome Membrane
	Molecular Function	Protein Binding Small GTPase Binding Protein Dimerization Activity Dynein Light Intermediate Chain Binding	Protein Binding Hydrolase Activity Phosphatidylinositol-4,5-bisphosphate 4-phosphatase Activity
	Biological Process	Epithelial Cell Morphogenesis Nitric Oxide Mediated Signal Transduction Protein Transport Cilium Assembly Protein Transport From Ciliary Membrane To Plasma Membrane	Lipid Metabolic Process Phospholipid Metabolic Process Response To Sterol Depletion Cholesterol Metabolic Process Lysosome Localization Phosphatidylinositol Dephosphorylation Proton-transporting V-type ATPase Complex Assembly Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of TORC1 Signaling
Pathways			PI5P Regulates TP53 Acetylation Synthesis of PIPs in the nucleus
Drugs
Diseases
GWAS		A body shape index ( 34021172) Educational attainment ( 25201988) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		7 interacting genes: APPBP2 DSCAM MOSPD3 NTAQ1 PIP4P1 SEC22A TRAF3IP3	5 interacting genes: EPN2 PLEKHB2 RILPL1 SLC10A6 YAP1
Entrez ID		353116	90809
HPRD ID		13435	12660
Ensembl ID		ENSG00000188026	ENSG00000165782
Uniprot IDs		A0A1B0GVV3 Q5EBL4	Q86T03
PDB IDs			8OQH
Enriched GO Terms of Interacting Partners?		Post-embryonic Retina Morphogenesis In Camera-type Eye Netrin Receptor Binding Protein-N-terminal Asparagine Amidohydrolase Activity Protein-N-terminal Glutamine Amidohydrolase Activity Phosphatidylinositol-4,5-bisphosphate 4-phosphatase Activity	Regulation Of Notch Signaling Pathway Positive Regulation Of Notch Signaling Pathway Enterocyte Differentiation Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport Lateral Mesoderm Development TEAD-YAP Complex Cardiac Muscle Tissue Regeneration Cell Morphogenesis Protein Transport From Ciliary Membrane To Plasma Membrane
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