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PIP4P1

Name phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1
Structure PDB 8OQH
Interactors 5 interactors: EPN2 PLEKHB2 RILPL1 SLC10A6 YAP1
GO Annotations Cellular Component
  • Nucleoplasm
  • Lysosome
  • Lysosomal Membrane
  • Endosome
  • Plasma Membrane
  • Membrane
  • Phagocytic Vesicle Membrane
  • Cytoplasmic Vesicle
  • Late Endosome Membrane
Molecular Function
  • Protein Binding
  • Hydrolase Activity
  • Phosphatidylinositol-4,5-bisphosphate 4-phosphatase Activity
Biological Process
  • Lipid Metabolic Process
  • Phospholipid Metabolic Process
  • Response To Sterol Depletion
  • Cholesterol Metabolic Process
  • Lysosome Localization
  • Phosphatidylinositol Dephosphorylation
  • Proton-transporting V-type ATPase Complex Assembly
  • Regulation Of Signal Transduction By P53 Class Mediator
  • Positive Regulation Of TORC1 Signaling
Pathways
  • PI5P Regulates TP53 Acetylation
  • Synthesis of PIPs in the nucleus
GWAS No GWAS studies recorded
Entrez ID 90809
HPRD ID 12660
Ensembl ID ENSG00000165782
Uniprot IDs Q86T03
PDB IDs 8OQH
GO Terms Enriched among Interactors ?
  • Regulation Of Notch Signaling Pathway
  • Positive Regulation Of Notch Signaling Pathway
  • Enterocyte Differentiation
  • Sodium-dependent Organic Anion Transmembrane Transporter Activity
  • Sodium-dependent Organic Anion Transport
  • Lateral Mesoderm Development
  • TEAD-YAP Complex
  • Cardiac Muscle Tissue Regeneration
  • Cell Morphogenesis
  • Protein Transport From Ciliary Membrane To Plasma Membrane

© Madhavi K. Ganapathiraju 2012-2026