DGAT2L6 and NDRG4

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		DGAT2L6	NDRG4
Name		diacylglycerol O-acyltransferase 2 like 6	NDRG family member 4
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Cytoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Basolateral Plasma Membrane Cell Projection Membrane
	Molecular Function	Diacylglycerol O-acyltransferase Activity Protein Binding O-acyltransferase Activity Transferase Activity Acyltransferase Activity	Molecular_function Protein Binding
	Biological Process	Lipid Metabolic Process Monoacylglycerol Biosynthetic Process Acylglycerol Acyl-chain Remodeling	Heart Looping Signal Transduction Visual Learning Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Negative Regulation Of Smooth Muscle Cell Migration Cell Differentiation Embryonic Heart Tube Development Vesicle Docking Negative Regulation Of Smooth Muscle Cell Proliferation Cardiac Muscle Cell Proliferation Cell Migration Involved In Heart Development Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Endocytic Recycling
Pathways		Acyl chain remodeling of DAG and TAG	None
GWAS		No GWAS studies recorded	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098 ) Electrocardiographic traits ( 20062063 ) Liver enzyme levels (alanine transaminase) ( 33972514 ) Oily fish consumption ( 32066663 ) Pork consumption ( 32066663 ) QT interval ( 19305408 19305409 22726844 ) Schizophrenia ( 29483656 )
Novel Interactors		None recorded	5 novel interactors: ADCY9 ALDH6A1 CMTM3 DHX38 NOL3
Interacting Genes		45 interacting genes: ABHD4 ABHD5 ACSF2 AQP6 ARFIP2 BNIP2 CIAO2A DIABLO ECPAS FARS2 FBXL19 FCER1G GAD2 GPR152 HSD17B11 MCEMP1 MPP1 MTERF4 MYG1 NAPB NDRG4 PBX3 PGRMC2 PITPNC1 REEP4 RNF144A RNF5 RUSF1 SCAND1 SCN3B SLC10A1 SLC10A6 SMG9 SNX4 STAR THAP4 TMED8 TMEM143 TMEM14B TMEM255B TMEM31 TMX2 TTPA TUFM WIPI2	37 interacting genes: AGTRAP APLNR ARFIP2 ARL6IP1 ATP5PF BCL2L13 CACFD1 CDR1 CIDEB CMTM5 COQ3 CPLX2 DERL3 DGAT2L6 ERGIC3 LEUTX LIME1 LRRC59 MAL2 MTIF3 PLP2 PRAF2 RABAC1 REEP6 RTN3 SCAMP1 SDR16C5 SFT2D2 SGK1 SIN3A SMPD2 SYNGR1 SYNGR3 SYP THAP4 TMEM208 YIF1A
Entrez ID		347516	65009
HPRD ID		13141	14817
Ensembl ID		ENSG00000184210	ENSG00000103034
Uniprot IDs		Q6ZPD8	A0A0S2Z5L7 A0A0S2Z5R7 B7Z9X4 Q9ULP0
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		None	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Synaptic Vesicle Vesicle-mediated Transport Endoplasmic Reticulum Tubular Network Formation Cytoplasmic Vesicle Endoplasmic Reticulum Tubular Network Membrane Organization Synaptic Vesicle Membrane Regulation Of Synaptic Vesicle Priming Protein Binding Regulation Of Short-term Neuronal Synaptic Plasticity Endoplasmic Reticulum Organization Synaptic Vesicle Membrane Organization Endoplasmic Reticulum Membrane Organization