ELOVL6

Description		ELOVL fatty acid elongase 6
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Fatty Acid Elongase Complex Membrane
	Molecular Function	Protein Binding Fatty Acid Elongase Activity Transferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Unsaturated Fatty Acid Biosynthetic Process Fatty Acid Elongation, Saturated Fatty Acid Sphingolipid Biosynthetic Process Fatty Acid Elongation Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongation, Polyunsaturated Fatty Acid Long-chain Fatty-acyl-CoA Biosynthetic Process Long-chain Fatty Acid Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process Positive Regulation Of Cold-induced Thermogenesis
Pathways		Activation of gene expression by SREBF (SREBP) Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 20732626) Benign prostatic hyperplasia ( 30988330) Liver enzyme levels (alkaline phosphatase) ( 33972514) Obesity-related traits ( 23251661) Serum alkaline phosphatase levels ( 33547301) Serum metabolite levels ( 33031748)
Interacting Genes		3 interacting genes: HMOX1 LCP2 RTP2
Entrez ID		79071
HPRD ID		13269
Ensembl ID		ENSG00000170522
Uniprot IDs		Q9H5J4
PDB IDs
Enriched GO Terms of Interacting Partners?		Heme Oxidation Smooth Muscle Hyperplasia Heme Oxygenase (decyclizing) Activity Wound Healing Involved In Inflammatory Response TCR Signalosome Cellular Response To Cisplatin Olfactory Receptor Binding Response To Cisplatin Smooth Muscle Adaptation Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Porphyrin-containing Compound Catabolic Process Erythrocyte Homeostasis Heme Catabolic Process Mast Cell Activation Negative Regulation Of Ferroptosis Low-density Lipoprotein Particle Clearance Regulation Of Ferroptosis Cellular Response To Arsenic-containing Substance Cellular Response To Cadmium Ion Positive Regulation Of Epithelial Cell Apoptotic Process Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Multicellular Organismal-level Iron Ion Homeostasis Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Detection Of Chemical Stimulus Involved In Sensory Perception Of Taste Plasma Lipoprotein Particle Clearance Response To Arsenic-containing Substance Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Myeloid Cell Homeostasis Endothelial Cell Proliferation Negative Regulation Of Macroautophagy Heme Metabolic Process Plasma Membrane Raft
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