RXFP4 and ACTR10

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		RXFP4	ACTR10
Description		relaxin family peptide/INSL5 receptor 4	actin related protein 10
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Extracellular Region Cytoplasm Cytosol Cytoskeleton Dynactin Complex Azurophil Granule Lumen Axon Cytoplasm Ficolin-1-rich Granule Lumen
	Molecular Function	G Protein-coupled Receptor Activity Galanin Receptor Activity Protein Binding	Protein Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Positive Regulation Of Feeding Behavior	Microtubule-based Movement Retrograde Axonal Transport Of Mitochondrion
Pathways		G alpha (i) signalling events Relaxin receptors	MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Neutrophil degranulation COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		A body shape index ( 34021172) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for body mass index ( 34021172)	Alcohol consumption ( 31358974) Brain morphology (MOSTest) ( 32665545) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		10 interacting genes: ACTR10 GAPDH GJA8 KNG1 MAGED1 QDPR RLN3 TSPAN3 TTC4 TTI1	7 interacting genes: ACTA1 DCTN4 HOMEZ KRT31 NAGK RXFP4 SLC13A1
Entrez ID		339403	55860
HPRD ID		16421	12420
Ensembl ID		ENSG00000173080	ENSG00000131966
Uniprot IDs		Q8TDU9	Q9NZ32
PDB IDs		7YJ4 7YK6 7YK7
Enriched GO Terms of Interacting Partners?			Structural Constituent Of Cytoskeleton Sarcomere Stress Fiber Sodium:sulfate Symporter Activity Monoatomic Anion:sodium Symporter Activity N-acetylglucosamine Kinase Activity N-acylmannosamine Kinase Activity N-acetylmannosamine Metabolic Process Muramyl Dipeptide Kinase Activity Skeletal Muscle Thin Filament Assembly Mesenchyme Migration Protein Linear Polyubiquitination Positive Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway N-acetylglucosamine Catabolic Process N-acetylneuraminate Catabolic Process Galanin Receptor Activity Secondary Active Sulfate Transmembrane Transporter Activity Dynactin Complex Striated Muscle Thin Filament Sulfate Transmembrane Transport UDP-N-acetylglucosamine Biosynthetic Process Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway N-acetylneuraminate Metabolic Process Positive Regulation Of Feeding Behavior Solute:sodium Symporter Activity UDP-N-acetylglucosamine Metabolic Process Regulation Of Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
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