PKD1P1 and UBA5

Number of citations of the paper that reports this interaction (PubMedID 21516116)
20

Data Source:
BioGRID (two hybrid)

		PKD1P1	UBA5
Description		polycystin 1, transient receptor potential channel interacting pseudogene 1	ubiquitin like modifier activating enzyme 5
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane
	Molecular Function		Nucleotide Binding Protein Binding ATP Binding Zinc Ion Binding Ubiquitin-like Modifier Activating Enzyme Activity Protein Homodimerization Activity Metal Ion Binding UFM1 Activating Enzyme Activity
	Biological Process		Erythrocyte Differentiation Megakaryocyte Differentiation Regulation Of Type II Interferon Production Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Neuromuscular Process Reticulophagy Protein Ufmylation Protein K69-linked Ufmylation
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		3 interacting genes: HMBOX1 TRAF4 UBA5	8 interacting genes: APEH GABARAPL2 OGT PKD1P1 TMEM132D UBE2D2 UBE2K UBE2L3
Entrez ID		339044	79876
HPRD ID			15598
Ensembl ID		ENSG00000244257	ENSG00000081307
Uniprot IDs			Q9GZZ9
PDB IDs			3GUC 3H8V 5HKH 5IA8 5IAA 5L95 6H77 6H78 6H8C 7NVK 7NW1 7OVC
Enriched GO Terms of Interacting Partners?		Telomere-telomerase Complex Assembly UFM1 Activating Enzyme Activity Thioesterase Binding Double-stranded Telomeric DNA Binding Ubiquitin-like Modifier Activating Enzyme Activity Protein K69-linked Ufmylation Protein Ufmylation Respiratory Tube Development Megakaryocyte Differentiation	Ubiquitin Conjugating Enzyme Activity Proteolysis Regulation Of Proteasomal Protein Catabolic Process Ubiquitin-protein Transferase Activity Protein Polyubiquitination Ubiquitin Protein Ligase Binding Mitophagy Regulation Of Protein Catabolic Process Regulation Of Proteolysis Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Proteasomal Protein Catabolic Process Autophagy Of Mitochondrion Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Catabolic Process Protein K48-linked Ubiquitination Omega Peptidase Activity Negative Regulation Of Protein Catabolic Process Protein O-acetylglucosaminyltransferase Activity Protein-containing Complex Disassembly Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Protein-containing Complex Organization Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Modification Process Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Free Ubiquitin Chain Polymerization Protein Ubiquitination Regulation Of Protein Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Macroautophagy Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Protein Ubiquitination Protein Modification Process Ubiquitin-protein Transferase Activator Activity Regulation Of Transcription By Glucose Positive Regulation Of Peptidyl-threonine Phosphorylation Cellular Response To Nitrogen Starvation Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Transferase Activity NSL Complex Post-translational Protein Modification Regulation Of Post-translational Protein Modification
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