TMEM119 and ODF4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM119	ODF4
Description		transmembrane protein 119	outer dense fiber of sperm tails 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane	Membrane
	Molecular Function		Protein Binding
	Biological Process	Ossification Osteoblast Differentiation Endochondral Ossification Spermatogenesis Positive Regulation Of Gene Expression Negative Regulation Of Myotube Differentiation Cell Differentiation Positive Regulation Of Bone Mineralization BMP Signaling Pathway Biomineral Tissue Development Positive Regulation Of Osteoblast Proliferation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Bone Resorption Spermatid Differentiation Positive Regulation Of Bone Development	Spermatogenesis Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Heel bone mineral density ( 30598549) Intraocular pressure ( 29235454 29617998 30054594) Optic disc size ( 31809533) Refractive error ( 32231278)	Mean corpuscular hemoglobin concentration ( 29403010)
Interacting Genes		7 interacting genes: AQP6 CERS4 ODF4 SLC10A1 SLC10A6 SLC71A2 TSHR	22 interacting genes: APP CACNG1 CD9 CDIPT CNIH3 DEFB103A DEFB103B EBP LAPTM4B MARCHF5 MEOX2 MS4A13 NINJ2 RUSF1 SACM1L SLC25A46 SLC38A7 TMEM119 TMEM239 TOMM6 TRARG1 YIPF6
Entrez ID		338773	146852
HPRD ID		11260	17658
Ensembl ID		ENSG00000183160	ENSG00000184650
Uniprot IDs		Q4V9L6	C3TX97 Q2M2E3
PDB IDs
Enriched GO Terms of Interacting Partners?		Bile Acid:sodium Symporter Activity Bile Acid And Bile Salt Transport PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Transmembrane Transport Symporter Activity Cellular Response To Thyrotropin-releasing Hormone Thyroid-stimulating Hormone Receptor Activity Thyroid-stimulating Hormone Signaling Pathway Response To Thyrotropin-releasing Hormone Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport Monocarboxylic Acid Transport Membrane Cellular Response To Glycoprotein Organic Hydroxy Compound Transport Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Sodium Ion Transport Sphingosine N-acyltransferase Activity Monoatomic Anion Channel Activity Renal Water Transport Ammonium Transmembrane Transport Ammonium Channel Activity Bile Acid Transmembrane Transporter Activity Basolateral Plasma Membrane Protein-hormone Receptor Activity Monoatomic Ion Transport Carboxylic Acid Transport Organic Acid Transport Water Channel Activity Carbon Dioxide Transport Lipid Transport Organic Anion Transport Water Transport One-carbon Compound Transport	Membrane Chemoattractant Activity Positive Chemotaxis CCR6 Chemokine Receptor Binding Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Defense Response To Gram-negative Bacterium
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