TMEM119

Description		transmembrane protein 119
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane
	Molecular Function
	Biological Process	Ossification Osteoblast Differentiation Endochondral Ossification Spermatogenesis Positive Regulation Of Gene Expression Negative Regulation Of Myotube Differentiation Cell Differentiation Positive Regulation Of Bone Mineralization BMP Signaling Pathway Biomineral Tissue Development Positive Regulation Of Osteoblast Proliferation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Bone Resorption Spermatid Differentiation Positive Regulation Of Bone Development
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Heel bone mineral density ( 30598549) Intraocular pressure ( 29235454 29617998 30054594) Optic disc size ( 31809533) Refractive error ( 32231278)
Interacting Genes		7 interacting genes: AQP6 CERS4 ODF4 SLC10A1 SLC10A6 SLC71A2 TSHR
Entrez ID		338773
HPRD ID		11260
Ensembl ID		ENSG00000183160
Uniprot IDs		Q4V9L6
PDB IDs
Enriched GO Terms of Interacting Partners?		Bile Acid:sodium Symporter Activity Bile Acid And Bile Salt Transport PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Transmembrane Transport Symporter Activity Cellular Response To Thyrotropin-releasing Hormone Thyroid-stimulating Hormone Receptor Activity Thyroid-stimulating Hormone Signaling Pathway Response To Thyrotropin-releasing Hormone Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport Monocarboxylic Acid Transport Membrane Cellular Response To Glycoprotein Organic Hydroxy Compound Transport Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Sodium Ion Transport Sphingosine N-acyltransferase Activity Monoatomic Anion Channel Activity Renal Water Transport Ammonium Transmembrane Transport Ammonium Channel Activity Bile Acid Transmembrane Transporter Activity Basolateral Plasma Membrane Protein-hormone Receptor Activity Monoatomic Ion Transport Carboxylic Acid Transport Organic Acid Transport Water Channel Activity Carbon Dioxide Transport Lipid Transport Organic Anion Transport Water Transport One-carbon Compound Transport
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