HSP90AA2P and PRDM14

Number of citations of the paper that reports this interaction (PubMedID 29178343)
51

Data Source:
BioGRID (pull down)

		HSP90AA2P	PRDM14
Description		heat shock protein 90 alpha family class A member 2, pseudogene	PR/SET domain 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Protein-containing Complex Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleus Nucleoplasm
	Molecular Function	Nucleotide Binding ATP Binding ATP Hydrolysis Activity Unfolded Protein Binding ATP-dependent Protein Folding Chaperone	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA Binding RNA Binding Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Chromatin DNA Binding Metal Ion Binding Methyltransferase Regulator Activity Histone Methyltransferase Binding
	Biological Process	Protein Folding Protein-RNA Complex Assembly Cellular Response To Heat Protein Stabilization	Negative Regulation Of Transcription By RNA Polymerase II Cell Morphogenesis Cell Fate Specification Inner Cell Mass Cell Fate Commitment Regulation Of Transcription By RNA Polymerase II Germ Cell Development Embryo Implantation Fibroblast Growth Factor Receptor Signaling Pathway Fertilization Regulation Of Gene Expression Stem Cell Population Maintenance Germ-line Stem Cell Population Maintenance Methylation Epigenetic Regulation Of Gene Expression Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Gene Expression, Epigenetic Homeostasis Of Number Of Cells Within A Tissue Positive Regulation Of Flagellated Sperm Motility Positive Regulation Of Stem Cell Population Maintenance
Pathways			Transcriptional regulation of pluripotent stem cells
Drugs
Diseases
GWAS			Schizophrenia ( 30285260) Testicular germ cell tumor ( 23666240 28604728 28604732)
Interacting Genes		2 interacting genes: EP300 PRDM14	67 interacting genes: ABI2 AKAP9 AQP1 ATPAF2 BAG4 BAHD1 BCAR3 BEX2 CARD10 CASP8 CDCA7L CHEK2 CREB5 DGCR6 DMRT3 DRC4 EED EIF4E2 ENKD1 ERBB2 EZH2 FAM83A GEM GLYCTK GPATCH2L HEXIM2 HOXB5 HOXC8 HSP90AA2P HSPA5 HSPB7 ID3 IDH1 KANK2 LNX1 MIA3 MRPL32 MYPOP PALB2 PATZ1 PAX2 PLEKHF2 PRKAB2 PRPF31 PSMA1 PTPRJ RAD51D RBM10 RCOR3 RUSC1 SAXO4 SCNM1 SNRPC SUZ12 TCAF1 TEAD4 TEKT4 TLE5 TRIM41 TSGA10 TTC32 TXK USP2 WDR25 ZNF250 ZNF587 ZNF835
Entrez ID		3324	63978
HPRD ID			11457
Ensembl ID			ENSG00000147596
Uniprot IDs			Q9GZV8
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptidyl-lysine Propionylation Chromatin DNA Binding Swimming Cell Fate Commitment Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity Methyltransferase Regulator Activity Histone H2B Acetyltransferase Activity Acetylation-dependent Protein Binding Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Protein Propionyltransferase Activity Histone H3K27 Acetyltransferase Activity Peptide Crotonyltransferase Activity Epigenetic Regulation Of Gene Expression N-terminal Peptidyl-lysine Acetylation Histone H3K18 Acetyltransferase Activity Thigmotaxis Peptide Lactyltransferase (CoA-dependent) Activity Inner Cell Mass Cell Fate Commitment Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Protein Oligomerization Germ-line Stem Cell Population Maintenance L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Positive Regulation Of TORC2 Signaling Positive Regulation Of T-helper 17 Cell Lineage Commitment Regulation Of Tubulin Deacetylation Histone H3 Acetyltransferase Activity Internal Peptidyl-lysine Acetylation Chromatin Remodeling Pre-mRNA Intronic Binding Positive Regulation Of T-helper 17 Cell Differentiation Regulation Of Protein Deacetylation Cellular Response To L-leucine N-terminal Protein Amino Acid Acetylation Internal Protein Amino Acid Acetylation Peptidyl-lysine Acetylation Regulation Of TORC2 Signaling Positive Regulation Of Cell Fate Commitment T-helper 17 Cell Lineage Commitment STAT Family Protein Binding Histone H4 Acetyltransferase Activity Positive Regulation Of Flagellated Sperm Motility Positive Regulation Of Cilium Movement TORC2 Signaling Regulation Of Cellular Response To Heat	Chromatin Silencing Complex Protein Binding Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Ubiquitin Protein Ligase Binding Oligodendrocyte Differentiation ESC/E(Z) Complex Facultative Heterochromatin Formation Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Glial Cell Differentiation Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Identical Protein Binding Regulation Of Primary Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Anoikis Pronucleus Sex Chromatin Negative Regulation Of Transcription By RNA Polymerase II
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