SFMBT1 and ACP1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SFMBT1	ACP1
Description		Scm like with four mbt domains 1	acid phosphatase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Cytoplasm Cytosol Cytoplasmic Side Of Plasma Membrane Sarcolemma Synapse Extracellular Exosome
	Molecular Function	Chromatin Binding Transcription Corepressor Activity Protein Binding Histone Binding	Acid Phosphatase Activity Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding Hydrolase Activity Phosphatase Activity SH3 Domain Binding
	Biological Process	Chromatin Organization Regulation Of DNA-templated Transcription Spermatogenesis Cell Differentiation Negative Regulation Of DNA-templated Transcription Negative Regulation Of Muscle Organ Development	Chemical Synaptic Transmission
Pathways
Drugs			Adenine 4-Nitrophenyl Phosphate
Diseases
GWAS		A body shape index ( 34021172) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Chronic kidney disease ( 29124443) Creatinine levels ( 29124443) Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) ( 30120083) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31152163 29124443) General cognitive ability ( 29844566) Gout ( 33832965 31578528) Haemorrhoidal disease ( 33888516) Hand grip strength ( 29691431) Height ( 28552196 31562340 31217584) Hip circumference ( 28552196) Hyperuricemia ( 29124443) Intelligence (MTAG) ( 29326435) Mental health study participation (completed survey) ( 31263887) Multiple sclerosis ( 31604244) Schizophrenia ( 28991256 23974872) Serum uric acid levels ( 30993211 29403010 29124443) Type 2 diabetes (age of onset) ( 28060188) Urate levels ( 23263486 31985003 31578528) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Blood protein levels ( 30072576) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Large artery stroke ( 28265093) Night sleep phenotypes ( 27126917) Plateletcrit ( 32888494) Refractive error ( 32231278)
Interacting Genes		12 interacting genes: ACP1 ATOSB CLNK HOXB9 PHC1 PHC2 PSMA1 SCMH1 SPANXN2 SRPK1 WWP2 ZCCHC10	16 interacting genes: BARD1 CTNNB1 EPHA2 EPHB1 EPHB2 ERBB2 FABP4 FNBP1L FYN INSR KDR LCK MRPL20 SFMBT1 SPTAN1 ZAP70
Entrez ID		51460	52
HPRD ID		09539	08881
Ensembl ID		ENSG00000163935	ENSG00000143727
Uniprot IDs		Q9UHJ3	A0A140VK37 P24666 Q59EH3
PDB IDs			1XWW 3N8I 4Z99 4Z9A 4Z9B 5JNR 5JNS 5JNT 5KQG 5KQL 5KQM 5KQP 5PNT 6Y2V 6Y2W 7KH8 7UW6
Enriched GO Terms of Interacting Partners?		PcG Protein Complex PRC1 Complex Histone Binding	Protein Tyrosine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Peptidyl-tyrosine Phosphorylation Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Protein Kinase Activity Protein Phosphorylation Phosphorylation Kinase Activity Enzyme-linked Receptor Protein Signaling Pathway Regulation Of MAPK Cascade Dendritic Spine Organization Protein Modification Process Neuron Projection Organization Postsynapse Organization Regulation Of Multicellular Organismal Development Ephrin Receptor Signaling Pathway Ephrin Receptor Activity Regulation Of Intracellular Signal Transduction Regulation Of Cell Adhesion Response To Growth Factor Phosphatidylinositol 3-kinase Binding Cell Migration Transferase Activity Protein Metabolic Process Regulation Of Multicellular Organismal Process Cell Activation Phosphate-containing Compound Metabolic Process Membrane Raft ATP Binding Regulation Of Developmental Process Cell Motility Positive Regulation Of MAPK Cascade Positive Regulation Of Cell Junction Assembly Lymphocyte Activation Cell Surface Receptor Signaling Pathway Regulation Of Cell Junction Assembly Positive Regulation Of Cellular Component Organization Protein Autophosphorylation CD8 Receptor Binding Positive Regulation Of Cell Adhesion Cellular Response To Growth Factor Stimulus Regulation Of ERK1 And ERK2 Cascade Regulation Of Lymphocyte Activation Regulation Of Cellular Localization Animal Organ Morphogenesis T Cell Activation Optic Nerve Morphogenesis Hindbrain Tangential Cell Migration Non-membrane Spanning Protein Tyrosine Kinase Activity Cadherin Binding
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