HOXB2 and MNDA

Number of citations of the paper that reports this interaction (PubMedID 16458891)
0

Data Source:
HPRD (in vitro)

		HOXB2	MNDA
Description		homeobox B2	myeloid cell nuclear differentiation antigen
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Extracellular Region Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Azurophil Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	DNA Binding Double-stranded DNA Binding Protein Binding
	Biological Process	Morphogenesis Of An Epithelial Sheet Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Nervous System Development Anterior/posterior Pattern Specification Dorsal/ventral Pattern Formation Rhombomere 3 Development Rhombomere 4 Development Facial Nerve Structural Organization Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Skeletal System Morphogenesis Neural Nucleus Development	Activation Of Innate Immune Response Cellular Defense Response DNA Damage Response Negative Regulation Of B Cell Proliferation Cellular Response To Interferon-beta Positive Regulation Of Apoptotic Process B Cell Receptor Signaling Pathway
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis	Neutrophil degranulation
Drugs
Diseases
GWAS		Body mass index ( 26426971) Experiencing mood swings ( 29500382) Feeling hurt ( 29500382) Keratoconus ( 33649486) Primary tooth development (number of teeth) ( 20195514)	Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Perceived intensity of aspartame ( 31005972)
Interacting Genes		13 interacting genes: CREBBP DTX2 EP300 MID2 MNDA MORN3 NDOR1 PBX4 RCHY1 RUNX1T1 SOD1 UBASH3B ZNF410	14 interacting genes: CDK1 CDK2 CEBPA CRK FBXO7 HOXB2 MAPK8IP2 NSD3 PRMT6 PRMT7 RB1 RBL2 STAT3 TP53
Entrez ID		3212	4332
HPRD ID		00854	15932
Ensembl ID		ENSG00000173917	ENSG00000163563
Uniprot IDs		P14652	P41218 Q5VUU6
PDB IDs			2DBG 5H7Q 5WPZ 8I6K
Enriched GO Terms of Interacting Partners?		Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Histone H3K27 Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Zinc Ion Binding P53 Binding N-terminal Protein Amino Acid Acetylation Peptidyl-lysine Acetylation Nucleus Regulation Of Cellular Response To Heat Acetyltransferase Activity Cellular Response To Lectin Stimulatory C-type Lectin Receptor Signaling Pathway Transcription Coregulator Activity Histone Acetyltransferase Complex Protein-lysine-acetyltransferase Activity Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Histone Acetyltransferase Activity Protein Acetylation DNA-binding Transcription Factor Binding Phosphoprotein Binding Activation Of Innate Immune Response Tau Protein Binding Transcription Coactivator Binding Immune Response-activating Cell Surface Receptor Signaling Pathway Peptidyl-lysine Propionylation Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity NADPH-iron-sulfur [2Fe-2S] Protein Oxidoreductase Activity Protein Destabilization Canonical NF-kappaB Signal Transduction Damaged DNA Binding Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Cell Activation Transcription Coactivator Activity Positive Regulation Of Innate Immune Response Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Histone H2B Acetyltransferase Activity Acetylation-dependent Protein Binding Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Protein Propionyltransferase Activity Peptide Crotonyltransferase Activity Response To Antipsychotic Drug Action Potential Initiation	Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Phase Transition Transcription Regulator Complex Negative Regulation Of Cell Cycle Process Chromatin Organization Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cell Cycle G1/S Phase Transition Chromatin Remodeling Regulation Of Cell Cycle Regulation Of RNA Metabolic Process Regulation Of Cell Cycle Phase Transition Cyclin-dependent Protein Kinase Activity Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Mitotic Cell Cycle Intracellular Signaling Cassette Histone Methyltransferase Activity Regulation Of Lipid Kinase Activity Nucleoplasm Regulation Of Transcription By RNA Polymerase II Rb-E2F Complex Glial Cell Apoptotic Process Histone H4R3 Methyltransferase Activity Protein-arginine Omega-N Monomethyltransferase Activity Nucleus Histone Kinase Activity Chromatin Cell Population Proliferation RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of MiRNA Processing Regulation Of Cell Cycle Process Cellular Senescence DNA-templated Transcription Cellular Response To Xenobiotic Stimulus Regulation Of Hemopoiesis Protein-arginine N-methyltransferase Activity Mitotic DNA Damage Checkpoint Signaling Protein-containing Complex Mitotic DNA Integrity Checkpoint Signaling Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Ras Protein Signal Transduction Regulation Of Cell Development G1/S Transition Of Mitotic Cell Cycle
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?