HOXA11 and YY1

Number of citations of the paper that reports this interaction (PMID 16963455)
8

Data Source:
BioGRID (pull down, affinity chromatography technology)

		HOXA11	YY1
Gene Name		homeobox A11	YY1 transcription factor
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex Protein-DNA Complex Protein Complex	Nucleus Transcription Factor Complex Nuclear Matrix Ino80 Complex PcG Protein Complex
	Molecular Function	Sequence-specific DNA Binding	Four-way Junction DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Transcription Corepressor Activity RNA Binding Protein Binding Zinc Ion Binding Transcription Regulatory Region DNA Binding
	Biological Process	Skeletal System Development Metanephros Development Branching Involved In Ureteric Bud Morphogenesis Organ Induction Transcription, DNA-templated Multicellular Organismal Development Spermatogenesis Single Fertilization Mesodermal Cell Fate Specification Male Gonad Development Anatomical Structure Morphogenesis Anterior/posterior Pattern Specification Dorsal/ventral Pattern Formation Proximal/distal Pattern Formation Positive Regulation Of Cell Development Embryonic Limb Morphogenesis Positive Regulation Of Chondrocyte Differentiation Embryonic Forelimb Morphogenesis Embryonic Digit Morphogenesis Positive Regulation Of Transcription, DNA-templated Developmental Growth Uterus Development Embryonic Skeletal Joint Morphogenesis Cartilage Development Involved In Endochondral Bone Morphogenesis	Negative Regulation Of Transcription From RNA Polymerase II Promoter Double-strand Break Repair Via Homologous Recombination Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter RNA Localization Cellular Response To DNA Damage Stimulus Spermatogenesis Anterior/posterior Pattern Specification Response To UV-C Positive Regulation Of Gene Expression Cell Differentiation Cellular Response To UV Response To Prostaglandin F Camera-type Eye Morphogenesis Chromosome Organization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: CREBBP GMNN MEIS1 PGBD3 YY1	52 interactors: APP ATF2 ATF6 ATF7 BAP1 BRCA1 CDKN2A CREB1 CRKL E2F2 E2F3 EED EP300 FKBP1A FKBP3 GRN GTF2I HCFC1 HDAC2 HDAC3 HIST1H4A HOXA11 INO80 KAT2B MTA2 MYC NEDD4L NFKB1 NOTCH1 NPM1 NR1H2 PPIA PSMD9 RAF1 RYBP SAP30 SKP2 SLC39A7 SMAD1 SMAD2 SMAD3 SMURF2 SP1 SPRY1 SREBF1 TESK1 TFCP2 TP53 UHRF2 YAF2 ZNF232 ZRANB2
Entrez ID		3207	7528
HPRD ID		00846	02482
Ensembl ID		ENSG00000005073
Uniprot IDs		P31270	P25490
PDB IDs			1UBD 1ZNM
Enriched GO Terms of Interacting Partners?		Anatomical Structure Morphogenesis Camera-type Eye Morphogenesis Transcription From RNA Polymerase II Promoter Eye Morphogenesis Organ Morphogenesis Response To Prostaglandin F Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process N-terminal Peptidyl-lysine Acetylation Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Germ-line Stem Cell Maintenance Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Camera-type Eye Development Multicellular Organismal Development Eye Development Regulation Of Transcription From RNA Polymerase II Promoter Response To UV-C Regulation Of Gene Expression Anatomical Structure Development N-terminal Protein Amino Acid Acetylation Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Megakaryocyte Development Developmental Process Transcription, DNA-templated Sensory Organ Development RNA Biosynthetic Process Megakaryocyte Differentiation Definitive Hemopoiesis Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia N-terminal Protein Amino Acid Modification Lens Morphogenesis In Camera-type Eye Regulation Of Cellular Response To Heat Negative Regulation Of Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Organ Development Negative Regulation Of DNA Replication Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress RNA Metabolic Process Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Metabolic Process Cellular Response To UV Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter	Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Cellular Metabolic Process Gene Expression Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Gene Expression Regulation Of Gene Expression RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Cellular Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Cell Cycle Cellular Response To Growth Factor Stimulus DNA-templated Transcription, Initiation Response To Growth Factor Chromatin Organization Biosynthetic Process Cellular Response To Organic Substance Chromatin Modification Cell Cycle Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cellular Process Transforming Growth Factor Beta Receptor Signaling Pathway Notch Signaling Pathway Chromosome Organization
Tagcloud ?		ascl2 c4b dab2ip dlk1 eya4 fabp3 fzd9 gas7 hdac9 hoxa5 hoxa9 hoxb13 ihh ipf1 isl1 mest mme pax6 ptgs2 rassf1 rbp1 scgb3a1 sept5 serpina5 sox1 sox17 tbx1 tff1 thy1	activates activators adenylyl amp cbp clue creb cyclase cyclic depend discuss dissociates e2f1 exactly examples generating homologue implying machinery messenger myb myod neurotransmitter outline phosphorylates pka predisposition superfamily transported
Tagcloud (Difference) ?		ascl2 c4b dab2ip dlk1 eya4 fabp3 fzd9 gas7 hdac9 hoxa5 hoxa9 hoxb13 ihh ipf1 isl1 mest mme pax6 ptgs2 rassf1 rbp1 scgb3a1 sept5 serpina5 sox1 sox17 tbx1 tff1 thy1	activates activators adenylyl amp cbp clue creb cyclase cyclic depend discuss dissociates e2f1 exactly examples generating homologue implying machinery messenger myb myod neurotransmitter outline phosphorylates pka predisposition superfamily transported
Tagcloud (Intersection) ?