HLF and HNF4G

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		HLF	HNF4G
Gene Name		hepatic leukemia factor	hepatocyte nuclear factor 4, gamma
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleoplasm
	Molecular Function	DNA Binding Double-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding	Sequence-specific DNA Binding Transcription Factor Activity Steroid Hormone Receptor Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Skeletal Muscle Cell Differentiation Rhythmic Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Gene Expression Intracellular Receptor Signaling Pathway Endocrine Pancreas Development Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription, DNA-templated
Pathways			Regulation of beta-cell development Generic Transcription Pathway Regulation of gene expression in beta cells Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS		Urate levels ( 23263486)	Body mass index ( 20935630) Breast cancer ( 23535729) Obesity ( 23563607) Urate levels ( 23263486)
Protein-Protein Interactions		5 interactors: ARNTL CREBBP DBP HNF4G MYB	14 interactors: COPS5 EIF3I GAPDH HAX1 HLF NCOA1 NR0B2 NSD1 PNRC1 PNRC2 PRDX6 RANBP9 SRC TNNI2
Entrez ID		3131	3174
HPRD ID		00797	06909
Ensembl ID		ENSG00000108924	ENSG00000164749
Uniprot IDs		A8K1X8 Q16534 Q6FHS9	F1D8Q4 Q14541
PDB IDs			1LV2
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Rhythmic Process RNA Metabolic Process Positive Regulation Of Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Anatomical Structure Development Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Circadian Rhythm Transcription Initiation From RNA Polymerase II Promoter N-terminal Peptidyl-lysine Acetylation Developmental Process Nitrogen Compound Metabolic Process Oxidative Stress-induced Premature Senescence DNA-templated Transcription, Initiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Skeletal Muscle Cell Differentiation Germ-line Stem Cell Maintenance Stress-induced Premature Senescence Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Glucocorticoid Receptor Signaling Pathway Response To Redox State Regulation Of Type B Pancreatic Cell Development N-terminal Protein Amino Acid Acetylation Regulation Of Cell Differentiation Positive Regulation Of Histone H3-K9 Methylation	Regulation Of Gene Expression Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process RNA Biosynthetic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Biosynthetic Process Response To Progesterone Positive Regulation Of Transcription From RNA Polymerase II Promoter By Galactose Peptidyl-cysteine S-trans-nitrosylation Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Protein Kinase B Signaling RNA Metabolic Process Cellular Response To Progesterone Stimulus Deadenylation-independent Decapping Of Nuclear-transcribed MRNA Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Positive Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Cellular Response To Drug Peptidyl-amino Acid Modification Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Targeting To Mitochondrion Exosomal Secretion Response To Steroid Hormone Regulation Of Protein Kinase B Signaling Peptidyl-cysteine S-nitrosylation Positive Regulation Of Integrin Activation Positive Regulation Of Podosome Assembly Regulation Of Response To Drug Negative Regulation Of Mitochondrial Depolarization Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Negative Regulation Of Protein Homooligomerization Progesterone Receptor Signaling Pathway Positive Regulation Of Female Receptivity Regulation Of Podosome Assembly Cellular Response To Hormone Stimulus Male Mating Behavior Regulation Of Caveolin-mediated Endocytosis Mammary Gland Development
Tagcloud ?		adenovirus ahr arises arnt arnt2 aromatic aryl bhlh cbp conveys dioxin e1a extensively gst heterodimer hybrid hydrocarbon hydrocarbons interacted metabolizing methylcholanthrene partner pas pull sim somehow tetrachlorodibenzo transactivation translocator	5th adcy9 ancestry broader classes etiological exploiting extremes generalizable gnat2 h6pd height hip hs6st3 igfbp4 influencing loci mrps33p4 obesity overlap percentiles ppp2r2a rptor rsrc1 tails trait traits waist zzz3
Tagcloud (Difference) ?		adenovirus ahr arises arnt arnt2 aromatic aryl bhlh cbp conveys dioxin e1a extensively gst heterodimer hybrid hydrocarbon hydrocarbons interacted metabolizing methylcholanthrene partner pas pull sim somehow tetrachlorodibenzo transactivation translocator	5th adcy9 ancestry broader classes etiological exploiting extremes generalizable gnat2 h6pd height hip hs6st3 igfbp4 influencing loci mrps33p4 obesity overlap percentiles ppp2r2a rptor rsrc1 tails trait traits waist zzz3
Tagcloud (Intersection) ?