HLF

Description		HLF transcription factor, PAR bZIP family member
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm RNA Polymerase II Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Double-stranded DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Rhythmic Process
Pathways
Drugs
Diseases
GWAS		Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced) ( 24236485) Bipolar disorder ( 31043756 33263727) HDL cholesterol levels ( 32203549) Hematocrit ( 32888494) Hemoglobin ( 32888494) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494) Red blood cell count ( 32888494) Serum uric acid levels ( 30993211) Urate levels ( 23263486 31578528 31985003) Urate levels in obese individuals ( 25811787) Waist circumference ( 28552196) Weight ( 28552196) Zinc levels ( 26025379)
Novel Interacting Genes		5 novel interacting genes: ABCC3 CCDC59 MYL4 PPAN USO1
Interacting Genes		6 interacting genes: BMAL1 CREBBP DBP HNF4G MYB TET2
Entrez ID		3131
HPRD ID		00797
Ensembl ID		ENSG00000108924
Uniprot IDs		Q16534
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription By RNA Polymerase II Rhythmic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Factor Activity Positive Regulation Of RNA Metabolic Process Golgi Vesicle Docking Icosanoid Transmembrane Transporter Activity Glucuronoside Transmembrane Transporter Activity Glucuronoside Transport Energy Homeostasis Histone H3K27 Acetyltransferase Activity Positive Regulation Of Hepatic Stellate Cell Proliferation Myosin II Heavy Chain Binding Oxidative Stress-induced Premature Senescence Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Peptide Lactyltransferase (CoA-dependent) Activity Positive Regulation Of Testosterone Secretion DNA 5-methylcytosine Dioxygenase Activity
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