EHD3 and EHD1

Number of citations of the paper that reports this interaction (PubMedID 12121420)
0

Data Source:
HPRD (two hybrid, in vivo)

		EHD3	EHD1
Description		EH domain containing 3	EH domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Focal Adhesion Cilium Endosome Membrane Membrane Ciliary Pocket Membrane Endocytic Vesicle Cell Projection Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Ciliary Membrane	Cytoplasm Endosome Early Endosome Lipid Droplet Plasma Membrane Cilium Endosome Membrane Membrane Ciliary Pocket Membrane Endocytic Vesicle Platelet Dense Tubular Network Membrane Early Endosome Membrane Cell Projection Perinuclear Region Of Cytoplasm Presynaptic Active Zone Recycling Endosome Membrane Ciliary Membrane Extracellular Exosome Glutamatergic Synapse
	Molecular Function	Nucleotide Binding Nucleic Acid Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding Protein-macromolecule Adaptor Activity Metal Ion Binding	Nucleotide Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding Protein-macromolecule Adaptor Activity Small GTPase Binding Identical Protein Binding Cadherin Binding Metal Ion Binding
	Biological Process	Receptor Recycling Endocytosis Protein Transport Cell Projection Organization Endocytic Recycling Early Endosome To Golgi Transport Protein Homooligomerization Regulation Of Cardiac Muscle Contraction Cilium Assembly Protein Localization To Plasma Membrane Regulation Of Cardiac Muscle Cell Membrane Potential Golgi To Lysosome Transport Regulation Of Golgi Organization Regulation Of Cardiac Conduction	Intracellular Protein Transport Endocytosis Positive Regulation Of Cholesterol Storage Positive Regulation Of Neuron Projection Development Protein Transport Endosomal Transport Cell Projection Organization Neuron Projection Development Endocytic Recycling Low-density Lipoprotein Particle Clearance Cholesterol Homeostasis Protein Homooligomerization Cilium Assembly Protein Localization To Cilium Protein Localization To Plasma Membrane Positive Regulation Of Myoblast Fusion Cellular Response To Nerve Growth Factor Stimulus Positive Regulation Of Endocytic Recycling
Pathways		Factors involved in megakaryocyte development and platelet production	Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Estradiol levels ( 22675492) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494) Male-pattern baldness ( 28196072) Mean platelet volume ( 22139419 32888494 27863252 24026423 19820697) Metabolite levels ( 23823483) Monocyte count ( 32888494) Neutrophil count ( 32888494) Platelet count ( 27863252 32888494 22139419) Platelet distribution width ( 27863252 32888494) Plateletcrit ( 27863252 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 27863252 32888494) White blood cell count ( 32888494)
Interacting Genes		4 interacting genes: ARL6IP1 EHD1 SNAP29 SNCA	13 interacting genes: AP2A1 EHBP1 EHD3 HSPB1 IGF1R MICAL1 MUL1 OGT PACSIN2 RAB11FIP2 RBSN RFFL SNAP29
Entrez ID		30845	10938
HPRD ID		16170	09325
Ensembl ID		ENSG00000013016	ENSG00000110047
Uniprot IDs		Q9NZN3	A0A024R571 B2R5U3 Q9H4M9
PDB IDs			2JQ6 2KFF 2KFG 2KFH 2KSP
Enriched GO Terms of Interacting Partners?		Ciliary Pocket Membrane Synaptic Vesicle Priming Ciliary Membrane Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Regulation Of Amine Transport Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Membrane Organization Organelle Organization Cellular Component Assembly Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Transport Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Dopamine Metabolic Process Exocytosis Regulation Of Serotonin Uptake Positive Regulation Of L-glutamate Import Across Plasma Membrane Mitochondrial ATP Synthesis Coupled Electron Transport Presynapse Cuprous Ion Binding Protein Complex Oligomerization Protein-containing Complex Organization Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Dopamine Uptake Involved In Synaptic Transmission Response To Growth Factor Negative Regulation Of Catecholamine Metabolic Process Cellular Response To Growth Factor Stimulus Response To Iron(II) Ion Dopamine Biosynthetic Process Protein-containing Complex Assembly Regulation Of Dopamine Uptake Involved In Synaptic Transmission Vesicle-mediated Transport Negative Regulation Of Cellular Respiration Cell Projection Negative Regulation Of Oxidative Phosphorylation Cilium Assembly Cilium Organization Establishment Of Protein Localization Autophagosome Membrane Docking Positive Regulation Of Endocytic Recycling Positive Regulation Of Cholesterol Storage Platelet Dense Tubular Network Membrane Sec61 Translocon Complex	Intracellular Protein Localization Vesicle-mediated Transport Protein Transport Endosome Establishment Of Protein Localization Recycling Endosome Membrane Plasma Membrane Ciliary Pocket Membrane Protein Kinase Binding Endocytosis Golgi To Lysosome Transport Cilium Endosome Membrane Import Into Cell Post-Golgi Vesicle-mediated Transport Early Endosome To Golgi Transport Regulation Of Golgi Organization Golgi To Vacuole Transport Cytosolic Transport Membrane Establishment Of Localization In Cell Negative Regulation Of Protein Kinase C Signaling Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Ciliary Membrane Cytosol Regulation Of Cellular Component Organization Cellular Response To Glucose Stimulus Golgi Vesicle Transport Small GTPase Binding Intracellular Transport P53 Binding Cellular Response To Carbohydrate Stimulus Sulfur Oxidation Hippocampal Mossy Fiber Expansion Cell Projection Early Endosome Negative Regulation Of Intracellular Signal Transduction Protein Kinase C Inhibitor Activity Insulin-like Growth Factor Receptor Activity Protein Kinase Complex Intracellular Glucose Homeostasis Insulin Receptor Activity Protein O-acetylglucosaminyltransferase Activity TRAM-dependent Toll-like Receptor 4 Signaling Pathway F-actin Monooxygenase Activity Negative Regulation Of Cytokine-mediated Signaling Pathway Negative Regulation Of Response To Cytokine Stimulus Retrograde Transport, Endosome To Golgi Positive Regulation Of Cold-induced Thermogenesis
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