EHD1 and EHD3

Number of citations of the paper that reports this interaction (PMID 12121420)
24

Data Source:
HPRD (two hybrid, in vivo)

		EHD1	EHD3
Gene Name		EH-domain containing 1	EH-domain containing 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Lipid Particle Plasma Membrane Endosome Membrane Membrane Platelet Dense Tubular Network Membrane Early Endosome Membrane Recycling Endosome Membrane Extracellular Vesicular Exosome	Nucleus Cytoplasm Plasma Membrane Focal Adhesion Endosome Membrane Endocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Membrane
	Molecular Function	Calcium Ion Binding Protein Binding ATP Binding GTP Binding Rab GTPase Binding	Nucleic Acid Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding
	Biological Process	Intracellular Protein Transport Endocytosis Blood Coagulation Positive Regulation Of Cholesterol Storage Neuron Projection Development Endocytic Recycling Low-density Lipoprotein Particle Clearance Cholesterol Homeostasis Protein Homooligomerization Positive Regulation Of Myoblast Fusion Cellular Response To Nerve Growth Factor Stimulus Positive Regulation Of Endocytic Recycling	Blood Coagulation Endocytic Recycling Protein Homooligomerization Protein Targeting To Plasma Membrane Regulation Of Cardiac Muscle Cell Membrane Potential
Pathways		Factors involved in megakaryocyte development and platelet production	Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Estradiol levels ( 22675492) Mean platelet volume ( 22139419 19820697) Platelet counts ( 22139419)
Protein-Protein Interactions		12 interactors: ANKFY1 AP2A1 CLTC EHBP1 EHD3 IGF1R MICAL1 MICALL1 PLA2G4A RAB11FIP2 RBSN SNAP29	3 interactors: EHD1 RBSN SNAP29
Entrez ID		10938	30845
HPRD ID		09325	16170
Ensembl ID		ENSG00000110047
Uniprot IDs		B2R5U3 Q9H4M9	B4DFR5 Q9NZN3
PDB IDs		2JQ6 2KFF 2KFG 2KFH 2KSP
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Negative Regulation Of Hyaluronan Biosynthetic Process Endosomal Transport Establishment Of Localization In Cell Post-Golgi Vesicle-mediated Transport Protein Transport Establishment Of Protein Localization Cellular Localization Membrane Organization Endocytic Recycling Protein Localization Endocytosis Transport Golgi Vesicle Transport Intracellular Transport Vesicle Fusion Receptor-mediated Endocytosis Intracellular Protein Transport Inactivation Of MAPKK Activity Slow Endocytic Recycling Organelle Fusion Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Establishment Of Cell Polarity Endosomal Vesicle Fusion Golgi To Lysosome Transport Positive Regulation Of Pinocytosis Membrane Fusion Regulation Of Body Fluid Levels Cellular Protein Localization Platelet Activating Factor Biosynthetic Process Regulation Of Carbohydrate Metabolic Process Secretion Protein Targeting To Membrane Platelet Activating Factor Metabolic Process Insulin Secretion Involved In Cellular Response To Glucose Stimulus Establishment Or Maintenance Of Cell Polarity Endosome Localization Cardiolipin Acyl-chain Remodeling Sulfur Oxidation Positive Regulation Of Steroid Hormone Biosynthetic Process Exocrine Pancreas Development Golgi To Vacuole Transport Vesicle Organization Autophagic Vacuole Fusion Protein Localization To Endosome Regulation Of Cardiac Muscle Cell Membrane Potential Plasma Membrane Organization Synaptic Vesicle Priming	Positive Regulation Of Endocytic Recycling Regulation Of Endocytic Recycling Autophagic Vacuole Fusion Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Membrane Positive Regulation Of Myoblast Fusion Positive Regulation Of Cholesterol Storage Regulation Of Myoblast Fusion Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Low-density Lipoprotein Particle Clearance Endocytic Recycling Cellular Response To Nerve Growth Factor Stimulus Protein Complex Assembly Positive Regulation Of Myotube Differentiation Positive Regulation Of Lipid Storage Plasma Lipoprotein Particle Clearance Vesicle Targeting Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Vesicle Fusion Regulation Of Lipid Storage Regulation Of Myotube Differentiation Synaptic Vesicle Exocytosis Regulation Of Plasma Lipoprotein Particle Levels Positive Regulation Of Striated Muscle Cell Differentiation Macroautophagy Cholesterol Homeostasis Sterol Homeostasis Organelle Fusion Cellular Component Assembly Protein Localization Positive Regulation Of Muscle Cell Differentiation Establishment Of Localization In Cell Regulation Of Striated Muscle Cell Differentiation Neurotransmitter Secretion Synaptic Vesicle Transport Lipid Homeostasis Cellular Localization Membrane Fusion Cellular Response To Starvation Regulation Of Neurotransmitter Levels Regulation Of Muscle Cell Differentiation Autophagy Neurotransmitter Transport Cellular Response To Nutrient Levels Response To Starvation Establishment Of Vesicle Localization Endosomal Transport Vesicle Organization
Tagcloud ?		accurate complex2 date1 encode flowering h3k27me3 hd3a heading involve ld oslf photoperiod polycomb prc2 presently promotion repressed repression repressive repressor rft1 rice sd sdg711 sdg718 trimethylation z zeste	antagonistically arabidopsis atx1 calf date1 date3 date7 floral flowering ghd7 grain heading homeodomain modify oligonucleosomes ortholog oryza osgi osmads50 ostrx1 phytochrome protein1 rice sativa thaliana thymus trithorax trithorax1 trx
Tagcloud (Difference) ?		accurate complex2 encode h3k27me3 hd3a involve ld oslf photoperiod polycomb prc2 presently promotion repressed repression repressive repressor rft1 sd sdg711 sdg718 trimethylation z zeste	antagonistically arabidopsis atx1 calf date3 date7 floral ghd7 grain homeodomain modify oligonucleosomes ortholog oryza osgi osmads50 ostrx1 phytochrome protein1 sativa thaliana thymus trithorax trithorax1 trx
Tagcloud (Intersection) ?		date1 flowering heading rice