EHD3

Description		EH domain containing 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Focal Adhesion Cilium Endosome Membrane Membrane Ciliary Pocket Membrane Endocytic Vesicle Cell Projection Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Ciliary Membrane
	Molecular Function	Nucleotide Binding Nucleic Acid Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding Protein-macromolecule Adaptor Activity Metal Ion Binding
	Biological Process	Receptor Recycling Endocytosis Protein Transport Cell Projection Organization Endocytic Recycling Early Endosome To Golgi Transport Protein Homooligomerization Regulation Of Cardiac Muscle Contraction Cilium Assembly Protein Localization To Plasma Membrane Regulation Of Cardiac Muscle Cell Membrane Potential Golgi To Lysosome Transport Regulation Of Golgi Organization Regulation Of Cardiac Conduction
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Estradiol levels ( 22675492) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494) Male-pattern baldness ( 28196072) Mean platelet volume ( 22139419 32888494 27863252 24026423 19820697) Metabolite levels ( 23823483) Monocyte count ( 32888494) Neutrophil count ( 32888494) Platelet count ( 27863252 32888494 22139419) Platelet distribution width ( 27863252 32888494) Plateletcrit ( 27863252 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 27863252 32888494) White blood cell count ( 32888494)
Interacting Genes		4 interacting genes: ARL6IP1 EHD1 SNAP29 SNCA
Entrez ID		30845
HPRD ID		16170
Ensembl ID		ENSG00000013016
Uniprot IDs		Q9NZN3
PDB IDs
Enriched GO Terms of Interacting Partners?		Ciliary Pocket Membrane Synaptic Vesicle Priming Ciliary Membrane Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Regulation Of Amine Transport Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Membrane Organization Organelle Organization Cellular Component Assembly Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Transport Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Dopamine Metabolic Process Exocytosis Regulation Of Serotonin Uptake Positive Regulation Of L-glutamate Import Across Plasma Membrane Mitochondrial ATP Synthesis Coupled Electron Transport Presynapse Cuprous Ion Binding Protein Complex Oligomerization Protein-containing Complex Organization Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Dopamine Uptake Involved In Synaptic Transmission Response To Growth Factor Negative Regulation Of Catecholamine Metabolic Process Cellular Response To Growth Factor Stimulus Response To Iron(II) Ion Dopamine Biosynthetic Process Protein-containing Complex Assembly Regulation Of Dopamine Uptake Involved In Synaptic Transmission Vesicle-mediated Transport Negative Regulation Of Cellular Respiration Cell Projection Negative Regulation Of Oxidative Phosphorylation Cilium Assembly Cilium Organization Establishment Of Protein Localization Autophagosome Membrane Docking Positive Regulation Of Endocytic Recycling Positive Regulation Of Cholesterol Storage Platelet Dense Tubular Network Membrane Sec61 Translocon Complex
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