HBZ and KRTAP10-9

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		HBZ	KRTAP10-9
Description		hemoglobin subunit zeta	keratin associated protein 10-9
Image			No pdb structure
GO Annotations	Cellular Component	Hemoglobin Complex Haptoglobin-hemoglobin Complex Extracellular Exosome	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Oxygen Carrier Activity Iron Ion Binding Protein Binding Oxygen Binding Heme Binding Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Carbon Dioxide Transport Oxygen Transport Erythrocyte Maturation Erythrocyte Development
Pathways			Keratinization
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Body mass index ( 26426971) Early cardiac repolarization ( 31600170) Hemoglobin ( 32888494) Hemoglobin levels ( 26366553) Mean corpuscular hemoglobin ( 27863252 29403010 32888494) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 27863252 29403010) Red blood cell count ( 29403010 32888494)
Interacting Genes		30 interacting genes: APP CARD10 CCNDBP1 CYSRT1 DOCK8 FGFR3 GOLGA6L9 HBB HBD HBE1 HBG2 HBM HBQ1 HNRNPD HNRNPK IKBKG KHDRBS2 KHDRBS3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 MTUS2 NBPF19 NOTCH2NLA NTAQ1 RBMY1A1 SP1 UPF2	239 interacting genes: ADAMTSL4 ALDH3B1 ALPI ANKS1A ARFGAP1 ATXN7L1 AVPI1 BCL6B BMP7 BRME1 C10orf62 C11orf87 C22orf39 CATIP CATSPER1 CBX2 CCDC26 CD300LG CDKL3 CHIC2 CHRD CHRNG CKS1B CLK4 CNNM3 CRCT1 CREB5 CST9L CXCL16 CYSRT1 DHRS1 DHX57 DMRT3 DOCK2 EIF4E2 EZH2 FAM124B FAM161A FAM74A4 FAM76B FARS2 FBXW5 GABARAPL1 GABARAPL2 GATA2 GLIDR GLP1R GLRX3 GNE GPATCH2L GSTP1 GUCD1 HBG1 HBZ HCK HES6 HOXA1 HOXB9 HOXC8 HPCAL1 HSBP1 HSD3B7 IGSF8 INPP5D IQUB ITGB4 ITGB5 KAT5 KIAA0040 KIF9 KLHL38 KRT20 KRT83 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP12-1 KRTAP12-3 KRTAP26-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LUZP4 MAB21L3 MAPKBP1 MAZ MED30 MEOX2 MOBP MT1DP MXI1 MYPOP NAXD NBPF19 NECTIN3 NKD1 NOTCH2NLA NPBWR2 NPDC1 NPPB NR1D2 NUFIP2 OTX1 PCSK5 PDE9A PDGFRB PGAP2 PGLS PIGS PIN1 PLSCR1 POU4F2 PRKAA2 PRKAB2 PRPF31 PTGER3 PTPMT1 PVR RAB7A RASD1 RHNO1 RSPO2 SCARB1 SCNM1 SEMA3B SHFL SLC23A1 SLC6A20 SMARCE1 SMCP SPACA9 SPATA3 SPATA31J1 SPATA8 SPG7 SPRY1 SPRY2 STK16 TBC1D16 TBC1D23 TBC1D26 TEDC2 TGOLN2 THAP10 TLE5 TNFRSF6B TNP2 TRIM41 TRIM42 TXNDC5 TYMSOS TYRO3 UTP23 VGLL3 WNT11 WT1 WT1-AS XCL2 YIPF3 YY1 ZBTB24 ZBTB38 ZBTB9 ZFYVE26 ZNF124 ZNF155 ZNF165 ZNF20 ZNF251 ZNF264 ZNF275 ZNF286A ZNF317 ZNF319 ZNF417 ZNF433 ZNF439 ZNF440 ZNF473 ZNF490 ZNF491 ZNF497 ZNF524 ZNF564 ZNF572 ZNF578 ZNF581 ZNF587 ZNF599 ZNF625 ZNF688 ZNF696 ZNF697 ZNF699 ZNF764 ZNF774 ZNF777 ZNF792 ZNF80 ZNF837 ZNF844 ZNF860 ZSCAN21 ZSCAN26
Entrez ID		3050	386676
HPRD ID		00794	11195
Ensembl ID		ENSG00000130656	ENSG00000221837
Uniprot IDs		P02008	P60411
PDB IDs		1JEB 3W4U
Enriched GO Terms of Interacting Partners?		Hemoglobin Complex Haptoglobin-hemoglobin Complex Oxygen Carrier Activity Oxygen Transport Oxygen Binding Erythrocyte Development Myeloid Cell Development Hemoglobin Alpha Binding Carbon Dioxide Transport Hemopoiesis Heme Binding One-carbon Compound Transport Keratin Filament Intermediate Filament Regulation Of MRNA Splicing, Via Spliceosome Blood Microparticle MRNA Binding Regulation Of MRNA Processing Regulation Of MRNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing Cell Development Positive Regulation Of Amyloid Precursor Protein Catabolic Process Telomeric DNA Binding	Intermediate Filament Keratin Filament Keratinization Epidermis Development DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Transcription By RNA Polymerase II Zinc Ion Binding DNA Binding Hair Cycle Tissue Development Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity Lung Growth
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