Wiki-Pi
About
Search
People
Updates
Search
CERS2 and SLC19A2
Number of citations of the paper that reports this interaction (PubMedID
40355756
)
172
Data Source:
BioGRID
(affinity chromatography technology, two hybrid)
CERS2
SLC19A2
Description
ceramide synthase 2
solute carrier family 19 member 2
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Plasma Membrane
Membrane
Molecular Function
DNA Binding
Protein Binding
N-acyltransferase Activity
Transferase Activity
Sphingosine N-acyltransferase Activity
Protein Binding
Folic Acid Transmembrane Transporter Activity
Thiamine Transmembrane Transporter Activity
Vitamin Transmembrane Transporter Activity
Biological Process
Lipid Metabolic Process
Sphingolipid Metabolic Process
Negative Regulation Of Schwann Cell Proliferation
Regulation Of Lipid Metabolic Process
Sphingolipid Biosynthetic Process
Response To Immobilization Stress
Ceramide Biosynthetic Process
Negative Regulation Of Axon Regeneration
Negative Regulation Of Schwann Cell Migration
Negative Regulation Of Schwann Cell Proliferation Involved In Axon Regeneration
Spermatogenesis
Thiamine Diphosphate Biosynthetic Process
Folic Acid Transport
Thiamine Transport
Pyridoxine Transport
Thiamine-containing Compound Metabolic Process
Vitamin Transport
Transmembrane Transport
Thiamine Transmembrane Transport
Pathways
Sphingolipid de novo biosynthesis
Vitamin B1 (thiamin) metabolism
Drugs
Diseases
GWAS
Apolipoprotein A1 levels (
32203549
)
Body mass index (
26426971
)
Caffeine consumption from coffee or tea (
33287642
)
Estimated glomerular filtration rate (
31015462
31152163
)
Facial attractiveness (female raters) (
30946739
)
Glycated hemoglobin levels (
28898252
34059833
)
HDL cholesterol (
30275531
)
HDL cholesterol levels (
32203549
)
Hip circumference adjusted for BMI (
34021172
)
LDL cholesterol (
24097068
)
LDL cholesterol levels (
28334899
)
Reticulocyte fraction of red cells (
27863252
)
Rhegmatogenous retinal detachment (
23585552
)
Plasma factor V levels in venous thrombosis (
31271701
)
Venous thromboembolism (
21980494
)
Interacting Genes
15 interacting genes:
ASGR1
ASGR2
ATP6V0C
CERS6
DRD2
HSP90AA1
IER3IP1
NFE2L2
PEX6
SLC19A2
SLC22A1
SLC39A1
TMBIM6
UBC
YIF1A
1 interacting genes:
CERS2
Entrez ID
29956
10560
HPRD ID
06080
04897
Ensembl ID
ENSG00000143418
ENSG00000117479
Uniprot IDs
Q96G23
A0A024R8Y5
A0A024R928
O60779
PDB IDs
8Z7Z
8Z80
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Cellular Response To Hypoxia
Asialoglycoprotein Receptor Activity
Regulation Of Cellular Response To Hypoxia
Transmembrane Transport
Ubiquitin Protein Ligase Binding
Thiamine Transmembrane Transporter Activity
Thiamine Transport
Thiamine Transmembrane Transport
Membrane
Fucose Binding
Catecholamine Uptake
Dopamine Uptake
Protein Unfolding
Azole Transmembrane Transport
Plasma Membrane
Pyrimidine-containing Compound Transmembrane Transport
Negative Regulation Of Cytosolic Calcium Ion Concentration
Vitamin Transmembrane Transport
Dopamine Transport
Neurotransmitter Reuptake
D-mannose Binding
Monoatomic Cation Transmembrane Transport
Endoplasmic Reticulum Membrane
Establishment Of Localization In Cell
Monoamine Transport
Neurotransmitter Uptake
Organic Hydroxy Compound Transport
Monoatomic Cation Transport
Monoatomic Ion Transmembrane Transport
COPII-coated ER To Golgi Transport Vesicle
Pattern Recognition Receptor Activity
Response To Cocaine
Vitamin Transport
CTP Binding
DATP Binding
Positive Regulation Of Glutathione Biosynthetic Process
Neuron Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Positive Regulation Of Interleukin-4-dependent Isotype Switching To IgE Isotypes
Positive Regulation Of CD4-positive, Alpha-beta T Cell Costimulation
T-helper 2 Cell Activation
Response To Nitrogen Dioxide
Monoatomic Ion Transport
Lateral Plasma Membrane
G Protein-coupled Receptor Complex
Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production
Carboxylic Acid Transport
Organic Acid Transport
Neurofibrillary Tangle Assembly
UTP Binding
Sulfonylurea Receptor Binding
Cholesterol Biosynthetic Process Via Lathosterol
Cholesterol Biosynthetic Process Via Desmosterol
C-5 Sterol Desaturase Activity
Delta7-sterol 5(6)-desaturase Activity
Negative Regulation Of Schwann Cell Proliferation Involved In Axon Regeneration
Negative Regulation Of Schwann Cell Migration
Negative Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I
Sphingosine N-acyltransferase Activity
Negative Regulation Of Glial Cell Migration
Negative Regulation Of Schwann Cell Proliferation
N-acyltransferase Activity
Negative Regulation Of Transcription By RNA Polymerase I
Negative Regulation Of Ferroptosis
Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I
Negative Regulation Of Axon Regeneration
Negative Regulation Of Neuron Projection Regeneration
Regulation Of Ferroptosis
Lipid Biosynthetic Process
Negative Regulation Of Glial Cell Proliferation
Regulation Of Glial Cell Migration
Response To Immobilization Stress
Decidualization
Regulation Of Axon Regeneration
Regulation Of Neuron Projection Regeneration
Cholesterol Biosynthetic Process
Sterol Biosynthetic Process
Regulation Of Transcription By RNA Polymerase I
Regulation Of Glial Cell Proliferation
Negative Regulation Of Gliogenesis
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Ceramide Biosynthetic Process
Endoplasmic Reticulum Membrane
Lipid Metabolic Process
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?