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DSE and CPSF3L
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
DSE
CPSF3L
Gene Name
dermatan sulfate epimerase
cleavage and polyadenylation specific factor 3-like
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Endoplasmic Reticulum
Golgi Apparatus
Integral Component Of Membrane
Cytoplasm
Integrator Complex
Blood Microparticle
Molecular Function
Chondroitin-glucuronate 5-epimerase Activity
Protein Binding
Hydrolase Activity
Biological Process
Carbohydrate Metabolic Process
Pathogenesis
Heparan Sulfate Proteoglycan Biosynthetic Process
Glycosaminoglycan Metabolic Process
Chondroitin Sulfate Metabolic Process
Chondroitin Sulfate Biosynthetic Process
Dermatan Sulfate Biosynthetic Process
Small Molecule Metabolic Process
SnRNA Processing
Pathways
MPS IIIB - Sanfilippo syndrome B
Diseases of glycosylation
Defective B4GALT7 causes EDS, progeroid type
MPS I - Hurler syndrome
MPS IX - Natowicz syndrome
Chondroitin sulfate/dermatan sulfate metabolism
Glycosaminoglycan metabolism
Defective SLC26A2 causes chondrodysplasias
Defective CHST14 causes EDS, musculocontractural type
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
Defective PAPSS2 causes SEMD-PA
MPS IIIA - Sanfilippo syndrome A
Myoclonic epilepsy of Lafora
Glycogen storage diseases
Defective CHST6 causes MCDC1
MPS IIID - Sanfilippo syndrome D
MPS IIIC - Sanfilippo syndrome C
Diseases associated with glycosaminoglycan metabolism
Mucopolysaccharidoses
Defective EXT2 causes exostoses 2
MPS II - Hunter syndrome
Defective B3GAT3 causes JDSSDHD
Defective CHST3 causes SEDCJD
Defective EXT1 causes exostoses 1, TRPS2 and CHDS
MPS IV - Morquio syndrome A
Dermatan sulfate biosynthesis
Defective CHSY1 causes TPBS
MPS IV - Morquio syndrome B
MPS VII - Sly syndrome
Metabolism of carbohydrates
MPS VI - Maroteaux-Lamy syndrome
Drugs
Diseases
GWAS
Protein-Protein Interactions
2 interactors:
ACSL4
CPSF3L
9 interactors:
ANXA7
CSNK2B
DSE
INTS9
MDFI
PLK1
PLSCR1
TK1
TRIP13
Entrez ID
29940
54973
HPRD ID
05807
13377
Ensembl ID
ENSG00000111817
ENSG00000127054
Uniprot IDs
B7Z765
Q9UL01
C9IYS7
Q5TA45
PDB IDs
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Prostaglandin Secretion
Negative Regulation Of Icosanoid Secretion
Response To Interleukin-15
Embryonic Process Involved In Female Pregnancy
Dendritic Spine Development
Long-chain Fatty-acyl-CoA Biosynthetic Process
Fatty-acyl-CoA Biosynthetic Process
Long-chain Fatty-acyl-CoA Metabolic Process
Negative Regulation Of Lipid Transport
SnRNA Processing
Regulation Of Fatty Acid Transport
SnRNA Metabolic Process
Triglyceride Biosynthetic Process
Fatty Acid Transport
Acyl-CoA Metabolic Process
Triglyceride Metabolic Process
Regulation Of Lipid Transport
Negative Regulation Of Ion Transport
Neutral Lipid Metabolic Process
Long-chain Fatty Acid Metabolic Process
Positive Regulation Of Cell Growth
Monocarboxylic Acid Transport
Dendrite Development
Regulation Of Anion Transport
Coenzyme Biosynthetic Process
Negative Regulation Of Secretion
Female Meiotic Division
Regulation Of Binding
Fetal Process Involved In Parturition
Regulation Of DNA Binding
Cellular Metabolic Process
Skeletal Muscle Cell Proliferation
Activation Of APC-Cdc20 Complex Activity
Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity
Polar Body Extrusion After Meiotic Divisions
Meiotic Nuclear Division
Response To Toxic Substance
Positive Regulation Of Protein Phosphorylation
Cell Proliferation
Phosphate-containing Compound Metabolic Process
Regulation Of Protein Kinase Activity
Phosphatidylserine Biosynthetic Process
Response To Cortisol
Thymidine Metabolic Process
Meiotic Cytokinesis
Activation Of Anaphase-promoting Complex Activity
Regulation Of Kinase Activity
Meiotic Cell Cycle
Positive Regulation Of Mitotic Metaphase/anaphase Transition
Positive Regulation Of Activin Receptor Signaling Pathway
Deoxyribonucleoside Monophosphate Biosynthetic Process
Adiponectin-activated Signaling Pathway
Metaphase/anaphase Transition Of Mitotic Cell Cycle
Chromosome Segregation
Membrane Organization
Positive Regulation Of Phosphorylation
Phosphorylation
Pyrimidine Nucleoside Salvage
Pyrimidine-containing Compound Salvage
Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway
Positive Regulation Of Protein Modification Process
Dermatan Sulfate Biosynthetic Process
Endothelial Tube Morphogenesis
Phospholipid Scrambling
Protein Localization To Chromatin
Response To Stress
Dermatan Sulfate Proteoglycan Biosynthetic Process
Cellular Water Homeostasis
Dermatan Sulfate Proteoglycan Metabolic Process
Female Meiosis I
Reproduction
Regulation Of Protein Phosphorylation
Positive Regulation Of Peptidyl-threonine Phosphorylation
Positive Regulation Of Chromosome Segregation
Response To Metal Ion
Tagcloud
?
a4
abstract
add2
adducin
binder
chimeric
coordination
cpsf160
cstf
depletion
dses
evidences
exclude
excluded
ftd
hek293
hypothesize
ltd
ltp
minigenes
participates
pas
polya
polyadenylation
substitution
sv40
synapse
tdp
tdp43
Tagcloud (Difference)
?
a4
abstract
add2
adducin
binder
chimeric
coordination
cpsf160
cstf
depletion
dses
evidences
exclude
excluded
ftd
hek293
hypothesize
ltd
ltp
minigenes
participates
pas
polya
polyadenylation
substitution
sv40
synapse
tdp
tdp43
Tagcloud (Intersection)
?