DSE

Gene Name		dermatan sulfate epimerase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Chondroitin-glucuronate 5-epimerase Activity
	Biological Process	Carbohydrate Metabolic Process Pathogenesis Heparan Sulfate Proteoglycan Biosynthetic Process Glycosaminoglycan Metabolic Process Chondroitin Sulfate Metabolic Process Chondroitin Sulfate Biosynthetic Process Dermatan Sulfate Biosynthetic Process Small Molecule Metabolic Process
Pathways		MPS IIIB - Sanfilippo syndrome B Diseases of glycosylation Defective B4GALT7 causes EDS, progeroid type MPS I - Hurler syndrome MPS IX - Natowicz syndrome Chondroitin sulfate/dermatan sulfate metabolism Glycosaminoglycan metabolism Defective SLC26A2 causes chondrodysplasias Defective CHST14 causes EDS, musculocontractural type Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective PAPSS2 causes SEMD-PA MPS IIIA - Sanfilippo syndrome A Myoclonic epilepsy of Lafora Glycogen storage diseases Defective CHST6 causes MCDC1 MPS IIID - Sanfilippo syndrome D MPS IIIC - Sanfilippo syndrome C Diseases associated with glycosaminoglycan metabolism Mucopolysaccharidoses Defective EXT2 causes exostoses 2 MPS II - Hunter syndrome Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective EXT1 causes exostoses 1, TRPS2 and CHDS MPS IV - Morquio syndrome A Dermatan sulfate biosynthesis Defective CHSY1 causes TPBS MPS IV - Morquio syndrome B MPS VII - Sly syndrome Metabolism of carbohydrates MPS VI - Maroteaux-Lamy syndrome
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: ACSL4 CPSF3L
Entrez ID		29940
HPRD ID		05807
Ensembl ID		ENSG00000111817
Uniprot IDs		B7Z765 Q9UL01
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Prostaglandin Secretion Negative Regulation Of Icosanoid Secretion Response To Interleukin-15 Embryonic Process Involved In Female Pregnancy Dendritic Spine Development Long-chain Fatty-acyl-CoA Biosynthetic Process Fatty-acyl-CoA Biosynthetic Process Long-chain Fatty-acyl-CoA Metabolic Process Negative Regulation Of Lipid Transport SnRNA Processing Regulation Of Fatty Acid Transport SnRNA Metabolic Process Triglyceride Biosynthetic Process Fatty Acid Transport Acyl-CoA Metabolic Process Triglyceride Metabolic Process Regulation Of Lipid Transport Negative Regulation Of Ion Transport Neutral Lipid Metabolic Process Long-chain Fatty Acid Metabolic Process Positive Regulation Of Cell Growth Monocarboxylic Acid Transport Dendrite Development Regulation Of Anion Transport Coenzyme Biosynthetic Process Negative Regulation Of Secretion
Tagcloud ?		a4 abstract add2 adducin binder chimeric coordination cpsf160 cstf depletion dses evidences exclude excluded ftd hek293 hypothesize ltd ltp minigenes participates pas polya polyadenylation substitution sv40 synapse tdp tdp43