TASP1

Description		taspase 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Threonine-type Endopeptidase Activity Peptidase Activity Hydrolase Activity Identical Protein Binding
	Biological Process	Proteolysis Positive Regulation Of DNA-templated Transcription Protein Maturation
Pathways		Formation of WDR5-containing histone-modifying complexes Formation of WDR5-containing histone-modifying complexes
Drugs
Diseases
GWAS		Chin dimples ( 27182965) Daytime sleep phenotypes ( 27126917) Night sleep phenotypes ( 27126917)
Novel Interacting Genes		1 novel interacting genes: MACROD2
Interacting Genes		4 interacting genes: APP FBXL17 GTF2A1 KMT2A
Entrez ID		55617
HPRD ID		07460
Ensembl ID		ENSG00000089123
Uniprot IDs		Q9H6P5
PDB IDs		2A8I 2A8J 2A8L 2A8M 6UGK 6VIN
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Positive Regulation Of Gene Expression, Epigenetic Amyloid-beta Complex PTB Domain Binding Regulation Of Neuronal Synaptic Plasticity Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Associative Learning Visual Behavior Regulation Of Response To Calcium Ion Cell Activation Involved In Immune Response Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Visual Learning Growth Cone Filopodium Learning Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Negative Regulation Of DNA Methylation-dependent Heterochromatin Formation Protein-cysteine Methyltransferase Activity ADP-ribosylglutamate Hydrolase Activity Peptidyl-glutamate ADP-deribosylation Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Synaptic Plasticity Axon Midline Choice Point Recognition Hemopoiesis Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Transcription Factor TFIIA Complex Negative Regulation Of Heterochromatin Formation O-acetyl-ADP-ribose Deacetylase Activity Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Macromolecule Metabolic Process Protein De-ADP-ribosylation Axon Choice Point Recognition
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