GTF2E2

Description		general transcription factor IIE subunit 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFIIE Complex Cytosol
	Molecular Function	TFIIH-class Transcription Factor Complex Binding DNA Binding RNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity
	Biological Process	Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Cognitive performance ( 20125193) Glaucoma (primary open-angle) ( 33627673) Mean corpuscular volume ( 32888494) Metabolite levels (X-11787) ( 23934736)
Interacting Genes		27 interacting genes: APP ATF7IP CCNH CDK7 ERCC3 ERCC6 EXOC8 FOS GRSF1 GTF2A1 GTF2B GTF2E1 GTF2F1 GTF2F2 GTF2H1 JUN KAT5 KLF5 MCC MDM2 MNAT1 NUP62 PICK1 SND1 SUPT16H TBP XPA
Entrez ID		2961
HPRD ID		01800
Ensembl ID		ENSG00000197265
Uniprot IDs		P29084
PDB IDs		1D8J 1D8K 5GPY 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 6O9L 7EG9 7EGA 7EGB 7EGC 7ENA 7ENC 7LBM 7NVR 7NVS 7NVT 7NVU 7NVY 7NVZ 7NW0 8BVW 8BYQ 8GXQ 8GXS 8S51 8S52 8S55 8S5N 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS
Enriched GO Terms of Interacting Partners?		Transcription Initiation At RNA Polymerase II Promoter DNA-templated Transcription Initiation Transcription By RNA Polymerase II DNA-templated Transcription RNA Polymerase II General Transcription Initiation Factor Activity Transcription Factor TFIIH Core Complex Nucleobase-containing Compound Biosynthetic Process Transcription Factor TFIIH Holo Complex Transcription Factor TFIID Complex Nucleoplasm RNA Metabolic Process Nucleic Acid Metabolic Process Positive Regulation Of RNA Metabolic Process DNA-templated Transcription Elongation Nucleotide-excision Repair Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Transcription Factor TFIIK Complex Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Transcription Elongation By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process CAK-ERCC2 Complex Positive Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II Core Promoter Sequence-specific DNA Binding Positive Regulation Of Biosynthetic Process Nucleus Positive Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II General Transcription Initiation Factor Binding Macromolecule Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Positive Regulation Of Metabolic Process Regulation Of Cell Cycle DNA Repair Regulation Of Metabolic Process Transcription Preinitiation Complex Regulation Of Cell Cycle Process Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Cellular Response To Stress DNA Damage Response
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