GSR and C11orf49

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GSR	C11orf49
Gene Name		glutathione reductase	chromosome 11 open reading frame 49
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Matrix Cytosol External Side Of Plasma Membrane Extracellular Vesicular Exosome	Nucleoplasm
	Molecular Function	Glutathione-disulfide Reductase Activity Electron Carrier Activity Mercury (II) Reductase Activity Mercury Ion Binding Flavin Adenine Dinucleotide Binding NADP Binding
	Biological Process	Response To Reactive Oxygen Species Glutathione Metabolic Process Nucleobase-containing Small Molecule Interconversion Small Molecule Metabolic Process Cell Redox Homeostasis Detoxification Of Mercury Ion Nucleobase-containing Small Molecule Metabolic Process Oxidation-reduction Process
Pathways
Drugs		Glutathione NADH Carmustine 3,6-Dihydroxy-Xanthene-9-Propionic Acid Nicotinamide-Adenine-Dinucleotide 3-Sulfinoalanine Glutathionylspermidine Disulfide 3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol Flavin-Adenine Dinucleotide Oxidized Glutathione Disulfide Meta-Nitro-Tyrosine 2-(2-PHENYL-3-PYRIDIN-2-YL-4,5,6,7-TETRAHYDRO-2H-ISOPHOSPHINDOL-1-YL)PYRIDINE 6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)HEXANOIC ACID
Diseases
GWAS			D-dimer levels ( 21502573)
Protein-Protein Interactions		3 interactors: C11orf49 OCM2 PJA1	12 interactors: ARHGEF15 CDC16 GSR PNMA5 PSMA1 RAB17 RAB29 RBM48 RPL8 RPS3A UBE3A UBQLN4
Entrez ID		2936	79096
HPRD ID		00704	08332
Ensembl ID		ENSG00000104687	ENSG00000149179
Uniprot IDs		P00390	B4DUV7 Q9H6J7
PDB IDs		1ALG 1BWC 1DNC 1GRA 1GRB 1GRE 1GRF 1GRG 1GRH 1GRT 1GSN 1K4Q 1XAN 2AAQ 2GH5 2GRT 3DJG 3DJJ 3DK4 3DK8 3DK9 3GRS 3GRT 3SQP 4GR1 4GRT 5GRT
Enriched GO Terms of Interacting Partners?			Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein Polyubiquitination Viral Process Regulation Of Protein Ubiquitination Regulation Of Proteolysis Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Rab Protein Signal Transduction Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Cellular Pigmentation Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Sperm Entry Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Synapse Organization Regulation Of Ubiquitin-protein Transferase Activity Catabolic Process Viral Transcription Regulation Of Synapse Structure Or Activity Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Negative Regulation Of Synapse Maturation Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Cotranslational Protein Targeting To Membrane Protein Targeting To ER Negative Regulation Of Protein Ubiquitination Establishment Of Protein Localization To Endoplasmic Reticulum Pigmentation Ubiquitin-dependent Protein Catabolic Process Retrograde Transport, Plasma Membrane To Golgi Modification-dependent Protein Catabolic Process Protein Localization To Endoplasmic Reticulum Positive Regulation Of Protein Ubiquitination Proteolysis Involved In Cellular Protein Catabolic Process Immunoglobulin Transcytosis In Epithelial Cells Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Protein Catabolic Process Translational Termination Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Protein Ubiquitination Nuclear-transcribed MRNA Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process MRNA Catabolic Process Protein Modification By Small Protein Conjugation Protein Catabolic Process
Tagcloud ?		blister conductance contributed corneum dc displayed dominated ducts electrical frequencies galvanic hence hz means measurements nail pores pure situ skin sources stratum substantial sweat totally typically unrealiable warts waves
Tagcloud (Difference) ?		blister conductance contributed corneum dc displayed dominated ducts electrical frequencies galvanic hence hz means measurements nail pores pure situ skin sources stratum substantial sweat totally typically unrealiable warts waves
Tagcloud (Intersection) ?