GSR

Description		glutathione-disulfide reductase
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol External Side Of Plasma Membrane Extracellular Exosome
	Molecular Function	Glutathione-disulfide Reductase (NADPH) Activity Electron Transfer Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, NAD(P) As Acceptor Flavin Adenine Dinucleotide Binding NADP Binding
	Biological Process	Glutathione Metabolic Process Cellular Response To Oxidative Stress Cell Redox Homeostasis Cellular Oxidant Detoxification
Pathways
Drugs		Glutathione NADH Carmustine 3,6-dihydroxy-xanthene-9-propionic acid 3-sulfino-L-alanine Glutathionylspermidine disulfide 3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol Flavin adenine dinucleotide Glutathione disulfide 3-nitro-L-tyrosine 2-(2-PHENYL-3-PYRIDIN-2-YL-4,5,6,7-TETRAHYDRO-2H-ISOPHOSPHINDOL-1-YL)PYRIDINE 6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)HEXANOIC ACID Cannabidiol Copper Medical Cannabis Nabiximols
Diseases
GWAS
Interacting Genes		5 interacting genes: CDC42 CSTPP1 OCM2 PJA1 RNF26
Entrez ID		2936
HPRD ID		00704
Ensembl ID		ENSG00000104687
Uniprot IDs		P00390 V9HW90
PDB IDs		1ALG 1BWC 1DNC 1GRA 1GRB 1GRE 1GRF 1GRG 1GRH 1GRT 1GSN 1K4Q 1XAN 2AAQ 2GH5 2GRT 3DJG 3DJJ 3DK4 3DK8 3DK9 3GRS 3GRT 3SQP 4GR1 4GRT 5GRT
Enriched GO Terms of Interacting Partners?		Ubiquitin Protein Ligase Activity
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