GRPR and GRP

Number of citations of the paper that reports this interaction (PMID 7838118)
9

Data Source:
HPRD (in vivo)

		GRPR	GRP
Gene Name		gastrin-releasing peptide receptor	gastrin-releasing peptide
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Region Extracellular Space
	Molecular Function	Bombesin Receptor Activity G-protein Coupled Peptide Receptor Activity	Receptor Binding Neuropeptide Hormone Activity
	Biological Process	G-protein Coupled Receptor Signaling Pathway Cell Proliferation Bombesin Receptor Signaling Pathway Regulation Of Cell Proliferation	Signal Transduction Neuropeptide Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events Signaling by GPCR Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding G alpha (q) signalling events Peptide hormone metabolism GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Incretin synthesis, secretion, and inactivation
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: GRP	4 interactors: DPP4 GRPR MEP1A MEP1B
Entrez ID		2925	2922
HPRD ID		02376	08845
Ensembl ID			ENSG00000134443
Uniprot IDs		P30550	P07492
PDB IDs
Enriched GO Terms of Interacting Partners?			Digestion Bombesin Receptor Signaling Pathway Negative Regulation Of Extracellular Matrix Disassembly Negative Regulation Of Extracellular Matrix Organization Proteolysis Regulation Of Cell-cell Adhesion Mediated By Integrin
Tagcloud ?		affine albino analogs attracted authors autoradiography biodistribution chelator coadministration coinjected derivatized dota endopeptidase frozen gastrin lu mer nep ninefold nmri nu phosphoramidon radioactivity radiolabeling radiopeptide releasing swiss xenografts	activators arsenite cations chaperones chemicals coordinate coupling cycling describing emphasized grp78 grps homeostatic hsp hsps integrative loading misfolding mobilizing modeled oxidants pertaining processing relates relating relationships thiol translation trigger
Tagcloud (Difference) ?		affine albino analogs attracted authors autoradiography biodistribution chelator coadministration coinjected derivatized dota endopeptidase frozen gastrin lu mer nep ninefold nmri nu phosphoramidon radioactivity radiolabeling radiopeptide releasing swiss xenografts	activators arsenite cations chaperones chemicals coordinate coupling cycling describing emphasized grp78 grps homeostatic hsp hsps integrative loading misfolding mobilizing modeled oxidants pertaining processing relates relating relationships thiol translation trigger
Tagcloud (Intersection) ?