GRP and GRPR

Number of citations of the paper that reports this interaction (PMID 7838118)
9

Data Source:
HPRD (in vivo)

		GRP	GRPR
Gene Name		gastrin-releasing peptide	gastrin-releasing peptide receptor
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Receptor Binding Neuropeptide Hormone Activity	Bombesin Receptor Activity G-protein Coupled Peptide Receptor Activity
	Biological Process	Signal Transduction Neuropeptide Signaling Pathway	G-protein Coupled Receptor Signaling Pathway Cell Proliferation Bombesin Receptor Signaling Pathway Regulation Of Cell Proliferation
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events Signaling by GPCR Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding G alpha (q) signalling events Peptide hormone metabolism GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Incretin synthesis, secretion, and inactivation	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: DPP4 GRPR MEP1A MEP1B	1 interactors: GRP
Entrez ID		2922	2925
HPRD ID		08845	02376
Ensembl ID		ENSG00000134443
Uniprot IDs		P07492	P30550
PDB IDs
Enriched GO Terms of Interacting Partners?		Digestion Bombesin Receptor Signaling Pathway Negative Regulation Of Extracellular Matrix Disassembly Negative Regulation Of Extracellular Matrix Organization Proteolysis Regulation Of Cell-cell Adhesion Mediated By Integrin
Tagcloud ?		activators arsenite cations chaperones chemicals coordinate coupling cycling describing emphasized grp78 grps homeostatic hsp hsps integrative loading misfolding mobilizing modeled oxidants pertaining processing relates relating relationships thiol translation trigger	affine albino analogs attracted authors autoradiography biodistribution chelator coadministration coinjected derivatized dota endopeptidase frozen gastrin lu mer nep ninefold nmri nu phosphoramidon radioactivity radiolabeling radiopeptide releasing swiss xenografts
Tagcloud (Difference) ?		activators arsenite cations chaperones chemicals coordinate coupling cycling describing emphasized grp78 grps homeostatic hsp hsps integrative loading misfolding mobilizing modeled oxidants pertaining processing relates relating relationships thiol translation trigger	affine albino analogs attracted authors autoradiography biodistribution chelator coadministration coinjected derivatized dota endopeptidase frozen gastrin lu mer nep ninefold nmri nu phosphoramidon radioactivity radiolabeling radiopeptide releasing swiss xenografts
Tagcloud (Intersection) ?