ANPEP and TM4SF1

Number of citations of the paper that reports this interaction (PMID 15812828)
12

Data Source:
HPRD (in vitro, in vivo)

		ANPEP	TM4SF1
Gene Name		alanyl (membrane) aminopeptidase	transmembrane 4 L six family member 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Lysosomal Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol Integral Component Of Plasma Membrane External Side Of Plasma Membrane Extracellular Vesicular Exosome	Integral Component Of Plasma Membrane
	Molecular Function	Virus Receptor Activity Aminopeptidase Activity Receptor Activity Metallopeptidase Activity Zinc Ion Binding	Molecular_function
	Biological Process	Angiogenesis Angiotensin Maturation Proteolysis Response To Virus Viral Process Cell Differentiation Cellular Protein Metabolic Process	Biological_process
Pathways		Peptide hormone metabolism Metabolism of Angiotensinogen to Angiotensins
Drugs		Ezetimibe Icatibant
Diseases
GWAS
Protein-Protein Interactions		1 interactors: TM4SF1	6 interactors: ANPEP DDR1 DNAJA1 HSPA8 SDCBP2 TUBA4A
Entrez ID		290	4071
HPRD ID		01055	01854
Ensembl ID		ENSG00000166825	ENSG00000169908
Uniprot IDs		P15144 Q59E93	P30408
PDB IDs		4FYQ 4FYR 4FYS 4FYT
Enriched GO Terms of Interacting Partners?			Protein Refolding Protein Folding 'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Locomotion Negative Regulation Of Fibril Organization Response To Heat Secretion Response To Unfolded Protein Smooth Muscle Cell-matrix Adhesion Regulation Of Fibril Organization Response To Temperature Stimulus Cellular Protein Metabolic Process Clathrin Coat Disassembly Cellular Localization Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Response To Stimulus Collagen-activated Signaling Pathway Transport DNA Damage Response, Detection Of DNA Damage Smooth Muscle Cell Migration Regulation Of Extracellular Matrix Disassembly Angiotensin Maturation Regulation Of Angiotensin Metabolic Process Negative Regulation Of JUN Kinase Activity Protein Metabolic Process Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin Movement Of Cell Or Subcellular Component Chaperone Mediated Protein Folding Requiring Cofactor Wound Healing, Spreading Of Cells Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Extracellular Matrix Organization Response To Stress Muscle Cell Migration Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Secretion By Cell Mammary Gland Lobule Development Mammary Gland Alveolus Development Positive Regulation Of RNA Splicing Viral Process Regulation Of Cellular Response To Heat Cellular Response To Stimulus Branching Involved In Mammary Gland Duct Morphogenesis Negative Regulation Of JNK Cascade Regulation Of Body Fluid Levels Wound Healing Peptide Hormone Processing Negative Regulation Of Stress-activated MAPK Cascade Peptidyl-tyrosine Autophosphorylation Establishment Of Localization In Cell
Tagcloud ?		bmp2 bmp6 bsp col il10 il6 itga6 ligament mcam mineralized mitf mmp2 msc mscs ocn orthodontic pdl predictability predictable premolar premolars prom1 regenerative rpl13a runt runx2 sialoprotein sox9 stemness	a549 adenocarcinoma ag almost blocking calu clearly consequently homologs igf1 igf1r l6 lung member mesenchymal migration overexpressing pten radiotherapy slightly tetraspanin therapeutics transmembrane tumorigenic unlike upregulated xenograft
Tagcloud (Difference) ?		bmp2 bmp6 bsp col il10 il6 itga6 ligament mcam mineralized mitf mmp2 msc mscs ocn orthodontic pdl predictability predictable premolar premolars prom1 regenerative rpl13a runt runx2 sialoprotein sox9 stemness	a549 adenocarcinoma ag almost blocking calu clearly consequently homologs igf1 igf1r l6 lung member mesenchymal migration overexpressing pten radiotherapy slightly tetraspanin therapeutics transmembrane tumorigenic unlike upregulated xenograft
Tagcloud (Intersection) ?