ANPEP

Name	alanyl aminopeptidase, membrane
Structure
Interactors	2 interactors: MTDH TM4SF1
GO Annotations	Cellular Component	Extracellular Space Lysosomal Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Plasma Membrane External Side Of Plasma Membrane Membrane Secretory Granule Membrane Extracellular Exosome
	Molecular Function	Virus Receptor Activity Aminopeptidase Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Alanyl Aminopeptidase Activity Hydrolase Activity Signaling Receptor Activity Metal Ion Binding Metalloaminopeptidase Activity
	Biological Process	Angiogenesis Angiotensin Maturation Proteolysis Cell Differentiation Peptide Catabolic Process Symbiont Entry Into Host Cell
Pathways	Metabolism of Angiotensinogen to Angiotensins Neutrophil degranulation
Drugs	Ezetimibe Icatibant
GWAS	Alanine aminotransferase levels ( 33547301 34315874 ) Aspartate aminotransferase levels ( 34315874 ) Gallstone disease ( 30504769 ) Intraocular pressure ( 29617998 ) Liver enzyme levels (alanine transaminase) ( 33972514 )
Entrez ID	290
HPRD ID	01055
Ensembl ID	ENSG00000166825
Uniprot IDs	P15144 Q59E93
PDB IDs	4FYQ 4FYR 4FYS 4FYT 5LHD 6ATK 6U7E 6U7F 6U7G 6XWD 7AEW 7VPQ 8WDE