SLC26A4-AS1 and GLS2

Number of citations of the paper that reports this interaction (PubMedID 32939012)
0

Data Source:
BioGRID (unspecified method)

		SLC26A4-AS1	GLS2
Description		SLC26A4 antisense RNA 1	glutaminase 2
Image		No pdb structure
GO Annotations	Cellular Component		Mitochondrion Mitochondrial Matrix
	Molecular Function		Glutaminase Activity Protein Binding Hydrolase Activity
	Biological Process		Amino Acid Metabolic Process Glutamate Biosynthetic Process Glutamine Metabolic Process L-glutamine Catabolic Process Regulation Of Apoptotic Process Reactive Oxygen Species Metabolic Process
Pathways			Glutamate Neurotransmitter Release Cycle TP53 Regulates Metabolic Genes Glutamate and glutamine metabolism
Drugs			Glutamic acid
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Adverse response to drug ( 30420678) Axial length ( 24144296) Estimated glomerular filtration rate ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Fasting glucose ( 34059833) Glycine levels ( 30837465) Lipoprotein (a) levels ( 33730874) Metabolic traits ( 21886157) Metabolite levels ( 22286219 22916037) Plasma free amino acid levels ( 30659259) Plasma free amino acid levels (adjusted for one other PFAA) ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259) Serum metabolite levels ( 23093944 31636271) Serum metabolite levels (CMS) ( 31636271)
Interacting Genes		19 interacting genes: ANXA2 CSTA DDX5 EEF1D EZR GLS2 GOLGA6L2 HP1BP3 HSPB1 LMNA LORICRIN MRC2 RPL22 RPS25 SERPINB3 TCP1 TRIM25 YBX3 ZNF326	14 interacting genes: CASK DLG1 DLG2 DLG3 DLG4 GRHPR PAG1 PATJ RALA RGS3 SLC26A4-AS1 SNTA1 TAX1BP3 XAF1
Entrez ID		286002	27165
HPRD ID			05901
Ensembl ID			ENSG00000135423
Uniprot IDs			A0A087X004 Q9UI32
PDB IDs			4BQM 5U0K 8SZL 8T0Z
Enriched GO Terms of Interacting Partners?		Cornified Envelope RNA Binding MRNA Transcription S100 Protein Binding Cytosol Peptide Cross-linking Protease Binding Regulation Of Primary Metabolic Process Nuclear Matrix	Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Neuromuscular Junction Ionotropic Glutamate Receptor Binding GMP Kinase Activity Receptor Localization To Synapse Receptor Clustering GDP Metabolic Process Protein Localization To Synapse Establishment Or Maintenance Of Cell Polarity Synaptic Membrane Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Protein Localization To Cell Junction Kinase Binding GMP Metabolic Process Postsynaptic Density Membrane Adherens Junction Cell Junction Nucleoside Monophosphate Metabolic Process Ribonucleoside Diphosphate Metabolic Process Juxtaparanode Region Of Axon Nucleoside Diphosphate Metabolic Process Basolateral Plasma Membrane Plasma Membrane Cellular Response To Potassium Ion Localization Within Membrane Purine Ribonucleotide Metabolic Process Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Ribonucleotide Metabolic Process Ribose Phosphate Metabolic Process Protein Localization To Membrane Chemical Synaptic Transmission Response To Potassium Ion Bicellular Tight Junction Neuron Projection Trans-synaptic Signaling Synaptic Signaling Purine Nucleotide Metabolic Process AMPA Glutamate Receptor Complex Protein Localization To Postsynaptic Membrane Protein Localization To Postsynapse Nucleotide Metabolic Process Regulation Of Sodium Ion Transmembrane Transport Intracellular Signal Transduction Protein Kinase Binding Purine-containing Compound Metabolic Process Cell-cell Junction Cell Adhesion P2Y1 Nucleotide Receptor Binding Hydroxypyruvate Reductase [NAD(P)H] Activity
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