DOK7 and MUSK

Number of citations of the paper that reports this interaction (PMID 16794080)
67

Data Source:
HPRD (in vivo)

		DOK7	MUSK
Gene Name		docking protein 7	muscle, skeletal, receptor tyrosine kinase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Cell Junction Neuromuscular Junction	Integral Component Of Plasma Membrane Cell Junction Neuromuscular Junction Receptor Complex Postsynaptic Membrane
	Molecular Function	Insulin Receptor Binding Protein Kinase Binding Phosphatidylinositol Binding	Protein Tyrosine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Binding ATP Binding
	Biological Process	Neuromuscular Junction Development Receptor Clustering Positive Regulation Of Protein Tyrosine Kinase Activity	Positive Regulation Of Protein Phosphorylation Regulation Of Transcription, DNA-templated Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organismal Development Neuromuscular Junction Development Memory Regulation Of Synaptic Growth At Neuromuscular Junction Positive Regulation Of Gene Expression Peptidyl-tyrosine Phosphorylation Cell Differentiation Extracellular Matrix Organization Positive Regulation Of Neuron Apoptotic Process Protein Autophosphorylation Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Protein Geranylgeranylation
Pathways			ECM proteoglycans
Drugs
Diseases
GWAS			Pulmonary function decline ( 22424883) Type 2 diabetes (dietary heme iron intake interaction) ( 23386860)
Protein-Protein Interactions		1 interactors: MUSK	4 interactors: COLQ DOK7 RAPSN SYNE1
Entrez ID		285489	4593
HPRD ID		08744	03190
Ensembl ID		ENSG00000175920	ENSG00000030304
Uniprot IDs		Q18PE1 Q8N1M3	O15146
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Geranylgeranylation Regulation Of Synaptic Growth At Neuromuscular Junction Skeletal Muscle Acetylcholine-gated Channel Clustering Postsynaptic Membrane Organization Receptor Clustering Neuromuscular Junction Development Regulation Of Synapse Assembly Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Neuron Death Regulation Of Synapse Organization Regulation Of Synapse Structure Or Activity Memory	Synaptic Transmission, Cholinergic Receptor Clustering Neuromuscular Junction Development Protein Localization Positive Regulation Of Neuromuscular Synaptic Transmission Synapse Organization Acetylcholine Catabolic Process In Synaptic Cleft Nuclear Matrix Anchoring At Nuclear Membrane Regulation Of Postsynaptic Membrane Organization Nuclear Matrix Organization Acetylcholine Catabolic Process Cellular Protein Localization Protein Localization To Membrane Skeletal Muscle Acetylcholine-gated Channel Clustering Cytoskeletal Anchoring At Nuclear Membrane Neurotransmitter Catabolic Process Maintenance Of Protein Location In Nucleus Synaptic Transmission Cellular Localization Asymmetric Protein Localization Establishment Of Nucleus Localization Neurotransmitter Metabolic Process Postsynaptic Membrane Organization Positive Regulation Of Protein Tyrosine Kinase Activity Membrane Organization Nucleus Localization Cell-cell Signaling Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Neuron Death Golgi Organization
Tagcloud ?			amine butylacetophenone butylxylene centrilobular cosmetics cyp1a cyp2b cyp3a cytochromes dinitro dosed equimolar gavage isozymes ketone microsomes mk musks mx nitroaromatic nitromusk noel observable p450 perfume phenobarbital toiletries trinitro xylene
Tagcloud (Difference) ?			amine butylacetophenone butylxylene centrilobular cosmetics cyp1a cyp2b cyp3a cytochromes dinitro dosed equimolar gavage isozymes ketone microsomes mk musks mx nitroaromatic nitromusk noel observable p450 perfume phenobarbital toiletries trinitro xylene
Tagcloud (Intersection) ?