EPHA6 and EFNA4

Number of citations of the paper that reports this interaction (PubMedID 10607706)
0

Data Source:
HPRD (in vitro, in vivo)

		EPHA6	EFNA4
Description		EPH receptor A6	ephrin A4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Dendrite	Extracellular Region Plasma Membrane Membrane Side Of Membrane
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Tyrosine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Ephrin Receptor Activity Transmembrane-ephrin Receptor Activity Protein Binding ATP Binding Kinase Activity Transferase Activity	Transmembrane-ephrin Receptor Activity Protein Binding Ephrin Receptor Binding
	Biological Process	Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Axon Guidance Ephrin Receptor Signaling Pathway	Cell-cell Signaling Axon Guidance Ephrin Receptor Signaling Pathway
Pathways		EPH-Ephrin signaling EPH-Ephrin signaling EPHA-mediated growth cone collapse EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells EPH-ephrin mediated repulsion of cells	EPH-Ephrin signaling EPH-Ephrin signaling EPHA-mediated growth cone collapse EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells EPH-ephrin mediated repulsion of cells
Drugs		Fostamatinib
Diseases
GWAS		Blood trace element (Cu levels) ( 23720494) Blood trace element (Zn levels) ( 23720494) Heel bone mineral density x serum urate levels interaction ( 34046847) Longevity ( 26912274) Obesity-related traits ( 23251661) Systolic blood pressure ( 29208002) Weight ( 28552196) White matter hyperintensity volume ( 33293549)	Adventurousness ( 30643258) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Prostate cancer ( 23535732) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		2 interacting genes: EFNA1 EFNA4	10 interacting genes: EPHA2 EPHA3 EPHA4 EPHA5 EPHA6 EPHA7 EPHA8 MAP2K4 TMEM147 TRARG1
Entrez ID		285220	1945
HPRD ID		13275	03224
Ensembl ID		ENSG00000080224	ENSG00000243364
Uniprot IDs		A0A0B4J1T8 B3KS12 Q9UF33	P52798
PDB IDs
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Binding Ephrin Receptor Signaling Pathway Side Of Membrane Neuron Projection Guidance Axon Guidance Endocardial Cushion To Mesenchymal Transition Involved In Heart Valve Formation Notochord Formation Endocardial Cushion To Mesenchymal Transition Negative Regulation Of Dendritic Spine Morphogenesis Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Neuron Projection Development Negative Regulation Of Thymocyte Apoptotic Process Negative Regulation Of Dendritic Spine Development Mitral Valve Morphogenesis Enzyme-linked Receptor Protein Signaling Pathway Cell-cell Signaling Cell Communication Regulation Of Thymocyte Apoptotic Process Signaling Transmembrane-ephrin Receptor Activity Positive Regulation Of Amyloid-beta Formation Atrioventricular Valve Morphogenesis Plasma Membrane Bounded Cell Projection Organization Negative Regulation Of T Cell Apoptotic Process Positive Regulation Of Amyloid Precursor Protein Catabolic Process Cardiac Epithelial To Mesenchymal Transition Positive Regulation Of Amide Metabolic Process Aortic Valve Morphogenesis Negative Regulation Of Lymphocyte Apoptotic Process Cell Projection Organization Regulation Of T Cell Apoptotic Process Regulation Of Dendritic Spine Morphogenesis Regulation Of Amyloid-beta Formation Negative Regulation Of Epithelial To Mesenchymal Transition Substrate Adhesion-dependent Cell Spreading Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Dendritic Spine Development Negative Regulation Of Leukocyte Apoptotic Process Heart Valve Morphogenesis Regulation Of Lymphocyte Apoptotic Process Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Amide Metabolic Process Epithelial To Mesenchymal Transition Mesenchymal Cell Differentiation Cell Surface Receptor Signaling Pathway Regulation Of Epithelial To Mesenchymal Transition Regulation Of Blood Vessel Endothelial Cell Migration	Ephrin Receptor Activity Transmembrane-ephrin Receptor Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Ephrin Receptor Signaling Pathway GPI-linked Ephrin Receptor Activity Protein Tyrosine Kinase Activity Protein Kinase Activity Kinase Activity Enzyme-linked Receptor Protein Signaling Pathway Neuron Projection Guidance Axon Guidance Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Neuron Projection Development Regulation Of GTPase Activity Cell Surface Receptor Signaling Pathway Dendrite ATP Binding Plasma Membrane Bounded Cell Projection Organization Fasciculation Of Motor Neuron Axon Fasciculation Of Sensory Neuron Axon Cell Projection Organization Nucleotide Binding Transferase Activity Growth Factor Binding Positive Regulation Of Protein Localization To Plasma Membrane Nephric Duct Morphogenesis Plasma Membrane Regulation Of Catalytic Activity Positive Regulation Of Protein Localization To Cell Periphery Neuromuscular Junction Regulation Of Synapse Pruning Positive Regulation Of Protein Localization To Membrane Schaffer Collateral - CA1 Synapse Regulation Of Protein Localization To Plasma Membrane Axonal Fasciculation Neuron Projection Fasciculation Regulation Of Cell Adhesion Regulation Of Protein Localization To Cell Periphery Cell Adhesion Signal Transduction Cell Migration Ephrin Receptor Binding Regulation Of Protein Localization To Membrane Regulation Of Cellular Localization System Development Cell Motility Protein Tyrosine Kinase Binding Nervous System Development Neuron Recognition Regulation Of Cell Adhesion Mediated By Integrin
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?