EFNA4 and EPHA6

Number of citations of the paper that reports this interaction (PMID 10607706)
11

Data Source:
HPRD (in vitro, in vivo)

		EFNA4	EPHA6
Gene Name		ephrin-A4	EPH receptor A6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Anchored Component Of Membrane	Cellular_component Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Transmembrane-ephrin Receptor Activity Protein Binding Ephrin Receptor Binding	Molecular_function Ephrin Receptor Activity ATP Binding
	Biological Process	Cell-cell Signaling Axon Guidance Osteoclast Differentiation Bone Remodeling Ephrin Receptor Signaling Pathway	Axon Guidance Biological_process Peptidyl-tyrosine Phosphorylation Ephrin Receptor Signaling Pathway
Pathways		EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling	EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)	Blood trace element (Cu levels) ( 23720494) Blood trace element (Zn levels) ( 23720494) Obesity-related traits ( 23251661)
Protein-Protein Interactions		8 interactors: EPHA2 EPHA3 EPHA4 EPHA5 EPHA6 EPHA7 EPHA8 MAP2K4	2 interactors: EFNA1 EFNA4
Entrez ID		1945	285220
HPRD ID		03224	13275
Ensembl ID		ENSG00000243364	ENSG00000080224
Uniprot IDs		P52798	B3KS12 D6RAL5 Q6UWM0 Q9UF33
PDB IDs
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Axon Guidance Peptidyl-amino Acid Modification Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Protein Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Morphogenesis Involved In Differentiation Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Cell Development Response To External Stimulus Neuron Development Phosphorylation Cell Morphogenesis Neuron Differentiation Cell Projection Organization Locomotion Movement Of Cell Or Subcellular Component Generation Of Neurons Phosphate-containing Compound Metabolic Process Neurogenesis Fasciculation Of Motor Neuron Axon Regulation Of Intracellular Signal Transduction Cell Surface Receptor Signaling Pathway Cellular Protein Modification Process Cell Differentiation Fasciculation Of Sensory Neuron Axon Nervous System Development Regulation Of MAPK Cascade Regulation Of Catalytic Activity Anatomical Structure Morphogenesis System Development Regulation Of Rho GTPase Activity Cellular Protein Metabolic Process Regulation Of Signal Transduction Regulation Of Rho Protein Signal Transduction Multicellular Organismal Development Anatomical Structure Development Regulation Of Signaling Signal Transduction Developmental Process Protein Metabolic Process Signaling	Ephrin Receptor Signaling Pathway Negative Regulation Of Dendritic Spine Morphogenesis Axon Guidance Endocardial Cushion To Mesenchymal Transition Involved In Heart Valve Formation Aortic Valve Morphogenesis Endocardial Cushion To Mesenchymal Transition Notochord Formation Mitral Valve Morphogenesis Negative Regulation Of Dendritic Spine Development Axonogenesis Mitral Valve Development Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Negative Regulation Of Dendrite Morphogenesis Neuron Projection Morphogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Morphogenesis Involved In Differentiation Notochord Morphogenesis Neuron Projection Development Cell Projection Morphogenesis Negative Regulation Of Dendrite Development Cell Part Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Heart Valve Formation Cell-cell Signaling Negative Regulation Of Epithelial To Mesenchymal Transition Neuron Development Atrioventricular Valve Morphogenesis Notochord Development Atrioventricular Valve Development Cell Morphogenesis Cardiac Epithelial To Mesenchymal Transition Neuron Differentiation Cell Projection Organization Regulation Of Dendritic Spine Morphogenesis Negative Regulation Of Stem Cell Differentiation Locomotion Heart Valve Morphogenesis Heart Valve Development Regulation Of Cell Adhesion Mediated By Integrin Substrate Adhesion-dependent Cell Spreading Osteoclast Differentiation Regulation Of Blood Vessel Endothelial Cell Migration Movement Of Cell Or Subcellular Component Regulation Of Dendritic Spine Development Generation Of Neurons Epithelial To Mesenchymal Transition Regulation Of Epithelial To Mesenchymal Transition Bone Remodeling
Tagcloud ?			a2bp1 abat cdh2 chmp2b cnvs crmp1 dementias dmrt1 duplications encompassing eo epha5 ermp1 evc evc2 fad flj35024 mapt microarrays pathogenicity pedigrees penetrant perhaps presenilin private psen1 psen2 underlie vldlr
Tagcloud (Difference) ?			a2bp1 abat cdh2 chmp2b cnvs crmp1 dementias dmrt1 duplications encompassing eo epha5 ermp1 evc evc2 fad flj35024 mapt microarrays pathogenicity pedigrees penetrant perhaps presenilin private psen1 psen2 underlie vldlr
Tagcloud (Intersection) ?